ID   A0A1I3ZAA3_9SPHN        Unreviewed;       962 AA.
AC   A0A1I3ZAA3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Two component regulator propeller {ECO:0000313|EMBL:SFK40943.1};
GN   ORFNames=SAMN03159338_4127 {ECO:0000313|EMBL:SFK40943.1};
OS   Sphingomonas sp. NFR04.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1566283 {ECO:0000313|EMBL:SFK40943.1, ECO:0000313|Proteomes:UP000198602};
RN   [1] {ECO:0000313|EMBL:SFK40943.1, ECO:0000313|Proteomes:UP000198602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NFR04 {ECO:0000313|EMBL:SFK40943.1,
RC   ECO:0000313|Proteomes:UP000198602};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FORV01000008; SFK40943.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3ZAA3; -.
DR   STRING; 1566283.SAMN03159338_4127; -.
DR   Proteomes; UP000198602; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR011110; Reg_prop.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR011123; Y_Y_Y.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   Pfam; PF07494; Reg_prop; 1.
DR   Pfam; PF07495; Y_Y_Y; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   TRANSMEM        726..746
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          659..718
FT                   /note="Two component regulator three Y"
FT                   /evidence="ECO:0000259|Pfam:PF07495"
FT   DOMAIN          765..827
FT                   /note="Signal transduction histidine kinase subgroup 3
FT                   dimerisation and phosphoacceptor"
FT                   /evidence="ECO:0000259|Pfam:PF07730"
FT   DOMAIN          871..960
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   962 AA;  103367 MW;  47AAA5F65C33E9DD CRC64;
     MLLVPAILAA APAIAQAPLQ RSIDQYNLRA WHLVDGAPPD IWALAQARDG FLYLGTGAGL
     YRFDGITFER VVPRSGRFAS RNITALLADP DGSLWIGHFD GQVSRLQGGR VTNFGAPNAA
     VEQFARGPDG TVWVAMSGVE GGLFRLGAAG IVRVGADQGM PAGRAASVVA GRDGAIWIAT
     ESDIRVLRPG ARRFLPVARS LYRARLAVAP DGQVWASGDP AHSPASGASG IRIAPLAAGM
     HPPAADRMGF TRDGALWRTL FAGGVLQTRN PGNAAPAFTR LTTKQGLPSL VAVPLLEDRE
     ANLWIGTNLG LFRLRPVSAA AALRVDDTVL GGFELAVTQD GTVYAANPHN LYRARPGEPL
     RWLRRFDQAI AMLEADGADL IVSLQDRLVR LHGGNFATLP APPLPGPAAT WARQGETQWI
     SVADVGVFQL AGRRWRAIGA TDQPANRLYT ASGAGGGNWF YGLDRLYRRD QTGLHAIAGD
     RVGSIALVSV GPAGTLVGGE LGLARLEQGR LRALPDSRVP EFGGITGIVQ APGGTVWING
     VRGLVQTSKA ALDAAFADPH APLQRQLFTA ADGLPGVAQQ GSPKTTAVRG GDGRIWVADN
     VGIGWIDPAR IVHNPLPPPV AILRLTANDR SYAEPHDVAL PAGTANLRIA YTALSLAEAE
     RVHFRYRLIG VDRDWIDAGT AREAYYANLG PGSWRFQVIA ANNDGVWNRE GATVTVTIAP
     HFYQTWWFRL LAIGAGAGLL WLLYAWRLRE QIARTRARAE AQLAERERIA RELHDTLLQS
     MQGLMLRFQA AAYATEPGSK AQTLIDSALE RADDVMMEAR DRVLALRRIT GPGDPQPLID
     ELARYLEEEG LLVTVTREGP PLRFSPEELE QILAIVQEAL ANVRRHAGTL LAQVRVDSRD
     GRLRIEIDDQ GRGIPPDVAA AGERPGHYGL KGMHERAAAL RGTLEVRRGA PIGTTVRLIV
     ER
//