ID   A0A1I4A4Z1_9PROT        Unreviewed;       999 AA.
AC   A0A1I4A4Z1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Glycerol dehydratase, cobalamin-independent, large subunit {ECO:0000313|EMBL:SFK51394.1};
GN   ORFNames=SAMN05216302_100832 {ECO:0000313|EMBL:SFK51394.1};
OS   Nitrosomonas aestuarii.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=52441 {ECO:0000313|EMBL:SFK51394.1, ECO:0000313|Proteomes:UP000199533};
RN   [1] {ECO:0000313|Proteomes:UP000199533}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm69 {ECO:0000313|Proteomes:UP000199533};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOSP01000008; SFK51394.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4A4Z1; -.
DR   STRING; 52441.SAMN05216302_100832; -.
DR   OrthoDB; 3251355at2; -.
DR   Proteomes; UP000199533; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR004184; PFL_dom.
DR   PANTHER; PTHR43641:SF2; DEHYDRATASE YBIW-RELATED; 1.
DR   PANTHER; PTHR43641; FORMATE ACETYLTRANSFERASE 3-RELATED; 1.
DR   Pfam; PF02901; PFL-like; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
DR   PROSITE; PS51554; PFL; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW   ProRule:PRU00493}; Reference proteome {ECO:0000313|Proteomes:UP000199533}.
FT   DOMAIN          59..838
FT                   /note="PFL"
FT                   /evidence="ECO:0000259|PROSITE:PS51554"
FT   DOMAIN          845..988
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000259|PROSITE:PS51149"
FT   REGION          202..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         963
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ   SEQUENCE   999 AA;  110882 MW;  6A837D0016DADEBA CRC64;
     MQTSNINRGG IHIDLEHGTA DTAAFNDKTA SYPIPNDAPD KIRTLNDLTL SHISLSDFPV
     VQAWRNQLFD PEWIPEVCDE LPRLLTEFLR KPKNDALPPI TQRSQALKHI FSHKTPFVKK
     SDLLPGQTTT SFVGPVVHMD MSGYCIWPEL DTIATRSQNP FKIKPEVARR FNEEIFPFWL
     ERRTVQEVAR YSDYDTADYA NDQRDTVDGG MADDQRSIDP PLKKRAGETP KCQELFERVA
     FYLTDKATAV SHTAPDFGRV LNYGMDALIA QLRQDIANGS TTGMTVDQKE FAEAVIAVYE
     GAKIYAEHLA EAAGHAGNNE LARICRRVPA KPAKTLAEAL TAVWICYHLL LQENTNFGLS
     PGRLDQTLND FYLNDWQQQP DDEARAAYTK HAVELMCHFF LRCSDHVPLS PETAEVLFAG
     SGSNQALTVG GTRYVNGKTV DAVNDMTYII LKATEMLSIR DPNVHARYHK DVHHRAPDGT
     PLGPGEISPY LKRICQVNLI TRATPALHGD VPVIHSMANY YARHDHVTME EALADAHDYA
     SIGCIEQNSD HKHYGHTGST LLVLPAVLEL AMFGGKHRSD GIGRNDPNLF YGKTEYTSSP
     LNEMDSMQQF IDSFRFQLDE MARHCVQFNN YLGRTLAKVR PSPLLSGLFD GPTNIPDGHG
     AKFRDLSSGG AKYNSSGVAI IGLADVIDSF CVIDALVFGG KMTADELVAA LNANFDPKRL
     PANKQTGFLK TLIELIKVQY PNDRQNKTRI TIKPERLQEC MDLIRVAPKY GAGVDKTPGG
     IFNNAMAVKY THLLTRMIQD VFFKYRTHRG GRYLTGYWSM TNHAGFGMLC KATPNGRLDN
     ASFASGITPC PGIVKANGEP VMLLDHMLSV ASVNPDTVQN GYTYNLSLTP RGKEYFNEDT
     DLFATYMKTF MDQDGVLVQL CVTSIEDFIA ADKAATAASQ TGAGEAEQKA LAPYKDLMIR
     VAGYSAYYVT LSPQMRQEII DRANFGMESG IEQHETAGV
//