ID   A0A1I4BKA2_9RHOB        Unreviewed;      1004 AA.
AC   A0A1I4BKA2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:SFK68311.1};
GN   ORFNames=SAMN04488036_1011046 {ECO:0000313|EMBL:SFK68311.1};
OS   Shimia haliotis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae.
OX   NCBI_TaxID=1280847 {ECO:0000313|EMBL:SFK68311.1, ECO:0000313|Proteomes:UP000198851};
RN   [1] {ECO:0000313|EMBL:SFK68311.1, ECO:0000313|Proteomes:UP000198851}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 28453 {ECO:0000313|EMBL:SFK68311.1,
RC   ECO:0000313|Proteomes:UP000198851};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; FOSZ01000001; SFK68311.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4BKA2; -.
DR   STRING; 1280847.SAMN04488036_1011046; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000198851; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          169..421
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          522..604
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          620..885
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          911..996
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   1004 AA;  108247 MW;  F35F2D671E46F1E4 CRC64;
     MSTRLTSGGR LLNKSKQVSF SFNGKKLTGY EGDTLASALL ANDQMLMGRS FKYHRPRGVV
     ASGAEEPNAL VNLGAGGKFE PNQRATTTEL YDGLSATSQN HWPSLEFDVG VANNYAARFL
     PAGFYYKTFM APRAAWKHVF EPIVRQSAGL GKAPKDRDAD RYEHYYAFFD VVVVGGGVAG
     LQAAKAAGQA GAKVLLMEQT AHWGGRAPVD GGEIDGKSAE DFVNATVAEL NAMDNVTIRS
     RMMGAGVYDH GYMLGYERLT DHAPAVAGPR HRLWRIRAKQ IVTATGAIER PLSFAGNDIP
     GVMLASAVRD YSVNFGVSSG DRTVVVTNND DAYRTAIALK NAGLEVPVIL DARATGGGAL
     ADEAKALGIR VENGKAIAKV KGGKRVTGVA ICAQAGEGAV LEEIMCDAVA MSGGWSPVVH
     LWSHCGGKLI WDETQAHFRP DPDRAPTSHD GNGFVVTAGT ASGPLLTGDV LADAQSAGIA
     VAKAAGFDGA AGAAPSAEAQ AEAGMEPVWL MPQGAGPKLR MKAWLDYQND VKVSDVKLAA
     QEGYESVEHT KRYTTLGMAT DQGKLSNING LAVLSDALNQ PIPATGTTTF RPPYTPISMG
     SIAGEARDEA FQPLRRTPIH DWHEANGAFF EPVGQWRRPY CFPRGSESHA DAVTREINQT
     RKSVGLLDAS TLGKIIVKGP DAGKFLDMMY TNMMSTLKPG KCRYGLMCNE NGFLIDDGVV
     ARIDEDTFLC HTTTGGAERI HGWMEDWLQC EWWDWEVFTA NVTEQYAQIA VVGPNARKVI
     EKLGGEMDVS KEGLAFMSWK DGKIGDFDAR AYRISFSGEL SYEIAVPASQ GRAFWDALLA
     AGEEFGIMPY GTEALHVMRA EKGFIMIGDE TDGTIIPQDL NMQWAISKKK EDFLGKRAQL
     RDHMASPDRW KLAGFETVDG SVIPDGSYIV ASGSNANNQR NVQGRVTSTY YSPTLDRGIA
     MGLLHNALDR MGEVVEFNKV DGSTVKAKVV DPVFYDKDGE KQNV
//