ID A0A1I4BZE0_9RHOB Unreviewed; 562 AA.
AC A0A1I4BZE0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SFK73459.1};
GN ORFNames=SAMN04488004_101237 {ECO:0000313|EMBL:SFK73459.1};
OS Loktanella salsilacus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Loktanella.
OX NCBI_TaxID=195913 {ECO:0000313|EMBL:SFK73459.1, ECO:0000313|Proteomes:UP000199550};
RN [1] {ECO:0000313|EMBL:SFK73459.1, ECO:0000313|Proteomes:UP000199550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16199 {ECO:0000313|EMBL:SFK73459.1,
RC ECO:0000313|Proteomes:UP000199550};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOTF01000001; SFK73459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4BZE0; -.
DR STRING; 195913.SAMN04488004_101237; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000199550; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199550};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..556
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 562 AA; 58690 MW; 78879C3D07D51180 CRC64;
MSSTPPGWIA ASVSRGQGDL RRAWLVLKLR GPSQVQFWFI ALFLGVASGA AAVAFKLGID
LIQRTVYGTD DPTHLHSFVA GLHWSQILII PIIGGLIVGL ILNRITGDGR VRSVADVIEG
AALYEGRVEV RKGLASAFAS LLTLSTGGSS GREGPVVHLA AVISTAICRV IRADGITGRD
LLGCAVAAAV SASFNAPIAG ALFALEVVLR HFAVHAFAPI VIASVAGTVV NRLWFGDITE
FILPRDTVLG FYVELPAFLI LGLICGLVAV VLMRSIFWAD SMGSRLQFSL NIPASLRPAG
AGALLGLIAI FFPHIIGVGY ETTSAALTGQ LVLSQAIIFV ILKVAAVAIT MGGRMGGGVF
SPALMIGALT GLAFGIVATG LFPAVSGSGT LYALAGMGAV AAAVLGAPIS TTLIVFELTG
DWQTGLAVMV AVSMSTALAS RLVDRSFFLT QLERRGVHLA AGPQAYLLGT FRVGTVMRFA
ADPRAAAEKA CWDMIEGGTW IDVNATLEQA MPIFEKGGHA FIPVVQMNEK GAAPDLRGAL
FQVDALRVLN RALADRAEEE HS
//
