ID A0A1I4CTN3_9PSEU Unreviewed; 306 AA.
AC A0A1I4CTN3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=8-oxo-dGTP diphosphatase {ECO:0000313|EMBL:SFK83980.1};
GN ORFNames=SAMN05421835_13724 {ECO:0000313|EMBL:SFK83980.1};
OS Amycolatopsis sacchari.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=115433 {ECO:0000313|EMBL:SFK83980.1, ECO:0000313|Proteomes:UP000199025};
RN [1] {ECO:0000313|EMBL:SFK83980.1, ECO:0000313|Proteomes:UP000199025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44468 {ECO:0000313|EMBL:SFK83980.1,
RC ECO:0000313|Proteomes:UP000199025};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582, ECO:0000256|RuleBase:RU003476}.
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DR EMBL; FORP01000037; SFK83980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4CTN3; -.
DR STRING; 115433.SAMN05421835_13724; -.
DR Proteomes; UP000199025; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03673; Ap6A_hydrolase; 1.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43222; NUDIX HYDROLASE 23; 1.
DR PANTHER; PTHR43222:SF2; NUDIX HYDROLASE 23, CHLOROPLASTIC; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003476};
KW Reference proteome {ECO:0000313|Proteomes:UP000199025}.
FT DOMAIN 1..126
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 306 AA; 32539 MW; CB9C083A9ACE3F9A CRC64;
MISAAGAVLW RDGGRGTEVA VVHRPRYDDW SLPKGKLDPG ETFPAAAVRE LAEETGFGVV
LGRRLRVVRY PVRGEEKVVE YYSARAGAGA FSPNEEVDEL RWLPVGEAAD VLTYETDVAV
LAEFRALPPA LGTLLLVRHA KAGKREEWNG DDDLRPLSPA GQRQAEALRR LLPLFGVDHV
FSAPRLRCVQ TVRGLAEDLG AEVVQEPLLA EEAYWAEPDR GLARLLAIAA GGGTPAVCSQ
GGVIPDVVSR LAAGLPLPTG KNGGVPSKKG SVWVLSFSAP GSNGGPRLVA ADYHPTALPH
PSATRS
//
