ID A0A1I4DC03_9PROT Unreviewed; 513 AA.
AC A0A1I4DC03;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetolactate synthase-1/2/3 large subunit {ECO:0000313|EMBL:SFK91022.1};
GN ORFNames=SAMN02745775_110118 {ECO:0000313|EMBL:SFK91022.1};
OS Falsiroseomonas stagni DSM 19981.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Falsiroseomonas.
OX NCBI_TaxID=1123062 {ECO:0000313|EMBL:SFK91022.1, ECO:0000313|Proteomes:UP000199473};
RN [1] {ECO:0000313|EMBL:SFK91022.1, ECO:0000313|Proteomes:UP000199473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19981 {ECO:0000313|EMBL:SFK91022.1,
RC ECO:0000313|Proteomes:UP000199473};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812}.
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DR EMBL; FOSQ01000010; SFK91022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4DC03; -.
DR STRING; 1123062.SAMN02745775_110118; -.
DR OrthoDB; 9773408at2; -.
DR Proteomes; UP000199473; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd02002; TPP_BFDC; 1.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR045229; TPP_enz.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR18968:SF86; ACETOLACTATE SYNTHASE LARGE SUBUNIT ILVX-RELATED; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000199473}.
FT DOMAIN 1..106
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 376..510
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
FT REGION 319..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 54084 MW; D7AFFB17E3559B24 CRC64;
MNGAESLVHT LLGAGVDTCF ANPGTSEMHF VAALDRIPGM RCVLGLQENV VTGMADGYFR
MAGKPAATLL HCGPGLANGL ANLHNARRAR SAIVNCVGDQ ATYHRPLDAQ LTADTEGFAR
AVSGWTRTVA RADEVGRDAA TAVQAAMTSP GQIATLILPS DTCWDEAPGG PAAALPVPAR
PQADPHAVRH AAKVLRERSN VLILLGGLAL TEEAQALAWR IGHATGASIL AEMSNAKVAR
GRGRMQLERV PYPADLAIEA LKPFTTIILV NSKAPVGFFA YPNKPSRHHR EDADIVLLTR
YEADPIQALT ALADELGAGP AAIPDPGPRP DPARGKPTPE GLAQTLAALM PENTVIADES
VSFGRGFYKF THNAPAHDWV HITGGAIGCG IPLATGAAIG APGRRVINLQ ADGSGMYTLQ
ALWTQARERL PITTIVISNR KYQILLGEYQ GVGANPGRTA LDMMDLGNPN LDWVKLANGM
GVEAARTGTL EGVADLMQQS FASETPFLIE MEV
//
