ID   A0A1I4DD63_9PSEU        Unreviewed;       466 AA.
AC   A0A1I4DD63;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=DNA polymerase-3 subunit epsilon {ECO:0000313|EMBL:SFK90953.1};
GN   ORFNames=SAMN05421835_14418 {ECO:0000313|EMBL:SFK90953.1};
OS   Amycolatopsis sacchari.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=115433 {ECO:0000313|EMBL:SFK90953.1, ECO:0000313|Proteomes:UP000199025};
RN   [1] {ECO:0000313|EMBL:SFK90953.1, ECO:0000313|Proteomes:UP000199025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44468 {ECO:0000313|EMBL:SFK90953.1,
RC   ECO:0000313|Proteomes:UP000199025};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FORP01000044; SFK90953.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4DD63; -.
DR   STRING; 115433.SAMN05421835_14418; -.
DR   Proteomes; UP000199025; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00027; BRCT; 1.
DR   CDD; cd06127; DEDDh; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR   PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199025};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        411..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        437..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..164
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00479"
SQ   SEQUENCE   466 AA;  48959 MW;  CD9FACF92EF840B5 CRC64;
     MPEVVDVLEL TRAGGYDATG LEFTAIGCRT TALRSGQLVE LAAVRTRADG STIGELSTLL
     NQESAPTLPE VLGYFTELLQ GAVLVAHNLA FVARFLGPEL DRYGIRVPAV DTLTTAKNTV
     RLPNYRLGTV ARSLGITDTR RDTALDDART GARVVTALVG VHGLRLTAWP RFGPLPQLVK
     SRPLAPRRAE PAAPAQGWTA ELPDRMPLTV PVDSPDPALE EAYLEVLGNA VAARQLTSAP
     PTGFGEDELR RIHTGFVHGM RTVAEADGIL TVEEVADLKA VATTLGVPGV VADVRPTERA
     DRPTRVLVLG RGADADELRA AVLTRGFQLA KNLTASVTHL VVCPDIAPTE PRLARAAEQG
     VTVLDAATAR RQLATPAPEA APAPPPVTRL APALAPAVTP ARPQGTNAAQ WGGRVITALG
     LVLVFVAAIA EFGGAPFAAG LVAFVLGAGI ALGGWYLGER WSVRSW
//