ID   A0A1I4DJE9_9ACTN        Unreviewed;       599 AA.
AC   A0A1I4DJE9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SFK92870.1};
GN   ORFNames=SAMN04488085_104397 {ECO:0000313|EMBL:SFK92870.1};
OS   Geodermatophilus ruber.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=504800 {ECO:0000313|EMBL:SFK92870.1, ECO:0000313|Proteomes:UP000199152};
RN   [1] {ECO:0000313|EMBL:SFK92870.1, ECO:0000313|Proteomes:UP000199152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45317 {ECO:0000313|EMBL:SFK92870.1,
RC   ECO:0000313|Proteomes:UP000199152};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FOSW01000004; SFK92870.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4DJE9; -.
DR   STRING; 504800.SAMN04488085_104397; -.
DR   InParanoid; A0A1I4DJE9; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000199152; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199152};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          287..562
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
FT   REGION          580..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   599 AA;  63740 MW;  7D7DEE43E9DFDAEC CRC64;
     MLRKPAPRWR LARLALLLTD LMSLYAGLTL AAAARYDGAL GRIDVGGLLV GTAVAAVVFV
     ALSLTLRLHQ GRYALASTDE VKALSLTLAA VALGGGAAVL VAGSPRPLPL SVPFLGAVLS
     FVLMLGCRLV IRRQREGALR PREGRPTLVF GAGDAGEQLV RSMLGDPASP YVPVGLLDDD
     PAKRHVRLRG VRMLGGRERI RVATETTGAE VLVIALPSAD SALVRDISTR ARATGLTVKV
     LPSLSDLLSR RVGIRDVRDI DIADLLGRRQ IDTNVDEIAG YLRGRRVLVT GAGGSIGSEL
     CRQIANYGPA ELMMLDRDES ALHAVQLSIR GQAWLDLPEV LLADIRDAEA VRALFGERRP
     DVVFHAAALK HLTMLEQYPA EGWKTNVLGT RNVLDAATAV GVSHFINVST DKAADPVSVL
     GRTKRMAERL TATYAQQNSG RFLSVRFGNV LGSRGSVLET FAAQIARGGP VTVTHPEVTR
     YFMTIPEAVQ LVIQAGAIGV GGEALVLDMG VPVRIADVAT SLIALEERPI NILFTGLRPG
     EKLHEDLFGA GEEDRRPVHP LISHVPVPAL EPEVLLGLGP TGPIEGSPPG GRARGMVSR
//