ID   A0A1I4F1D4_9BACL        Unreviewed;       662 AA.
AC   A0A1I4F1D4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Precorrin-3B C17-methyltransferase {ECO:0000313|EMBL:SFL11120.1};
GN   ORFNames=SAMN03159341_103273 {ECO:0000313|EMBL:SFL11120.1};
OS   Paenibacillus sp. 1_12.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1566278 {ECO:0000313|EMBL:SFL11120.1, ECO:0000313|Proteomes:UP000198699};
RN   [1] {ECO:0000313|EMBL:SFL11120.1, ECO:0000313|Proteomes:UP000198699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1_12 {ECO:0000313|EMBL:SFL11120.1,
RC   ECO:0000313|Proteomes:UP000198699};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004953}.
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DR   EMBL; FOTE01000003; SFL11120.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4F1D4; -.
DR   STRING; 1566278.SAMN03159341_103273; -.
DR   OrthoDB; 9772960at2; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000198699; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR   Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR   InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR   InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR   InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR   NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR   PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF01077; NIR_SIR; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR   SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR   PROSITE; PS00365; NIR_SIR; 1.
PE   4: Predicted;
KW   Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:SFL11120.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SFL11120.1}.
FT   DOMAIN          4..215
FT                   /note="Tetrapyrrole methylase"
FT                   /evidence="ECO:0000259|Pfam:PF00590"
FT   DOMAIN          536..639
FT                   /note="Nitrite/sulphite reductase 4Fe-4S"
FT                   /evidence="ECO:0000259|Pfam:PF01077"
FT   REGION          271..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..299
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   662 AA;  71634 MW;  C21272D0801314C3 CRC64;
     MAGKLLIVGF GPGSFEHITK RAREALQESD VIIGYNTYVD LISGLLSDQQ IVRTGMTEEV
     SRAQEAVRQA EAGKKVAVIS SGDAGVYGMA GLVYEVLIEK GWHPEDGVEV EIIPGISAIN
     SSASLLGAPI MHDSCTISLS DHLTPWELIE RRVEAAGQAD FVIALYNPRS GRRTRQIVET
     QRILLKYRSP ETPVGIVKSA YRDREHIVLT NLRDMLDHDI GMLTTVIIGN SSTMVYDGLM
     ITPRGYQRKY TLGADVQPLR PHQRLRQEAE PWALEQLPED PNDEHDDEEW ESNDEGDSLI
     EDIDDEEWDD EEDEVLAKNG GSLSAVSAVS PSSGAAGKPS LNYNEGIAAK AEAGKPYEGA
     LGKAKAVEYL GISTAAEPSA VAVAERHVSA DPLLLAMEAL QLVERRNGVA SVSINTTAPA
     VSVSGASVTA SAPAASSTAV TAGLFRQQSI FELAVSPGVA NKQFTAKQML TLAAVVGDKG
     SMEYTPHHQL IVRVPTDNPA EITQRLSMEG FLLAPIGDVA QVKACDFCNG EKGESIAYAE
     ELQAKLGGLG VPKEMRIGFN GCGMACYGAV NEDIGIVYRR GKFDLFLGGK TVGRNVHPAQ
     PVAEGIKPED LVATIERIMQ RYVTEGHPNE RFHKFFKRVK ELEGYRHQDL PVFTIENAIC
     GD
//