ID A0A1I4FAM1_9FIRM Unreviewed; 396 AA.
AC A0A1I4FAM1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=ribose-phosphate diphosphokinase {ECO:0000256|ARBA:ARBA00013247};
DE EC=2.7.6.1 {ECO:0000256|ARBA:ARBA00013247};
GN ORFNames=SAMN05216390_11211 {ECO:0000313|EMBL:SFL14978.1};
OS Lachnospiraceae bacterium KH1T2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1855374 {ECO:0000313|EMBL:SFL14978.1, ECO:0000313|Proteomes:UP000198626};
RN [1] {ECO:0000313|EMBL:SFL14978.1, ECO:0000313|Proteomes:UP000198626}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH1T2 {ECO:0000313|EMBL:SFL14978.1,
RC ECO:0000313|Proteomes:UP000198626};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|RuleBase:RU004324}.
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DR EMBL; FOSY01000012; SFL14978.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4FAM1; -.
DR STRING; 1855374.SAMN05216390_11211; -.
DR OrthoDB; 9777067at2; -.
DR Proteomes; UP000198626; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210:SF32; RIBOSE-PHOSPHATE DIPHOSPHOKINASE; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:SFL14978.1};
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727,
KW ECO:0000256|RuleBase:RU004324};
KW Reference proteome {ECO:0000313|Proteomes:UP000198626};
KW Transferase {ECO:0000313|EMBL:SFL14978.1}.
FT DOMAIN 16..166
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
FT DOMAIN 195..324
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 396 AA; 45294 MW; 1E735DEA53FC8172 CRC64;
MKINKYLENK MPAAPLKIIV MDSIKELGEQ VNNYLVEFRR EMNQPYHDSP AFEGYKMDNY
TINFSTPRFG SGEGKAVLNE TVRGKDLYIM LDVLNNSLTY KMHGYQNYYS PDDHFMDLKR
LIAATAGKAH RITVIMPFMY ESRQHKKTSR ESLDCALMLE DLYAMGVSRV ITFDAHDPSV
QNSAPLSGFD NFTPFYQFLR TLLANIGDLK IDKEHTLVIS PDEGALNRAV YFANVMGVDT
GMFYKRRDYT QVVDGKNPIV AHEFLGDNVE GKDVIIVDDM ISSGGSMIDT ARQLKKMNAK
RVFICCTFGI FTDGLEAFDD AYKKGYFDKV ICTNLTYRRP ELDERPYFLV ADMSKFLASI
IDFSNHDVSM EKVITPTEKI RKVLDRYNSI DGTIEE
//
