ID A0A1I4FEN6_9FIRM Unreviewed; 494 AA.
AC A0A1I4FEN6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:SFL15949.1};
GN ORFNames=SAMN05216390_11258 {ECO:0000313|EMBL:SFL15949.1};
OS Lachnospiraceae bacterium KH1T2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1855374 {ECO:0000313|EMBL:SFL15949.1, ECO:0000313|Proteomes:UP000198626};
RN [1] {ECO:0000313|EMBL:SFL15949.1, ECO:0000313|Proteomes:UP000198626}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH1T2 {ECO:0000313|EMBL:SFL15949.1,
RC ECO:0000313|Proteomes:UP000198626};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
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DR EMBL; FOSY01000012; SFL15949.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4FEN6; -.
DR STRING; 1855374.SAMN05216390_11258; -.
DR OrthoDB; 9763107at2; -.
DR Proteomes; UP000198626; Unassembled WGS sequence.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000198626}.
FT DOMAIN 5..80
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 101..421
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 112
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 494 AA; 54505 MW; F659A179CCFE9CB8 CRC64;
MDLMYKSTRD GNVCVKASQA ILKGLCDDGG LFVPERIPAL GKSLKELSEM DYRGVAYEVM
KEFITDFSED ELKSCIKNAY DEKFDTEEIA PLVEADGAFY LELFHGKTIA FKDMALSILP
HLMITSARKN NIENDIVILT ATSGDTGKAA LAGFADVKGT KIIVFYPKDG VSPVQKLQMV
TQKGDNTFVV GVDGNFDDCQ TGVKKMFSDA ALKDEIAAKG YQFSSANSIN IGRLVPQIVY
YVYAYTRLLK NEIITEGQEI NIVVPTGNFG NILAANYAKQ MGLPVKKLVC ASNENKVLFD
FFRTGTYDRN RQFILTSSPS MDILISSNLE RMIYHVSGDD PKATAGFMRE LKENGSYTIT
DKMREGLKDF CGYFASEADT AAKIKALYED TGYVIDTHTA VAGSAYDQYA KETSDETPTV
IASTASPFKF ARSVMTAIDK GYDAKDDFEL VDELSRIGNV EIPNAIDEIR NADVRHKTVC
SVDGMKAEVE KFLS
//
