ID A0A1I4GR82_9ACTN Unreviewed; 839 AA.
AC A0A1I4GR82;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN04488085_109120 {ECO:0000313|EMBL:SFL32010.1};
OS Geodermatophilus ruber.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Geodermatophilus.
OX NCBI_TaxID=504800 {ECO:0000313|EMBL:SFL32010.1, ECO:0000313|Proteomes:UP000199152};
RN [1] {ECO:0000313|EMBL:SFL32010.1, ECO:0000313|Proteomes:UP000199152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45317 {ECO:0000313|EMBL:SFL32010.1,
RC ECO:0000313|Proteomes:UP000199152};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FOSW01000009; SFL32010.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4GR82; -.
DR STRING; 504800.SAMN04488085_109120; -.
DR InParanoid; A0A1I4GR82; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000199152; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199152};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 499..826
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 839 AA; 90576 MW; F20E7EFB7E491011 CRC64;
MTAAEVVEAA APPVPDSFVR VRGAREHNLR DVDVDVPRDE LVAFTGVSGS GKSSLAFGTI
YAEAQRRYFE SVAPYARRLL NQAGVPQVDD ITGLPPAVAL QQRRGAPSSR STVGTLTTLS
NSLRMLFSRA GSYPPDATGV LDSDWFSPNT AVGACRECSG LGSVHEVTEQ TLVPDPSLSI
RDRAVAAWPG AWHGQNLRDI LVTLGHDIDR PWQDLPQEER DWILFTDEQP TVDIRPDRAA
VQADYTYRGT FSSARRHVLH TLANSTSPAM RERALRHVQT VDCPVCNGAR LRPEALAVTF
AGRTIAELAR LPVNELAAVL LHTAELTDPD AAWLSSESGE TTEVAVRIAR DLRERIMVLE
ELGLGYLSLD RTTTTLSPGE MQRLRLATQL RAGLFGVVYV LDEPSAGLHP ADAEPLLEVL
DRLKKSGNSL FVVEHDLDVV RRADWVVDVG PGAGQYGGRV LYSGPVDRLA GVDESVTRRF
LFGEERPPVR PARQPCGWLH LRGITRHNLR DVDADVPLGV FTAVTGVSGS GKSTLVTQVL
ADVVARRLGV RSAEDDDTGE DGPDAGMAVE AEGVEAFDRL VRVDQKPIGR TPRSNLATYT
GMFDAVRKLF AGTEEARRRG YTAGRFSFNV AGGRCETCQG EGFVAVELLF LPGTYAPCPT
CHGARYNPET LAVTWHGKNI AEVLALTVDE AAEFLAEVPA AARSLTTLQE VGLGYLRLGQ
PATELSGGEA QRIKLATELQ RGRRGHALYV LDEPTTGLHP ADVALLLRQL HRLVDQGNTV
VAVEHEMDVV VSADWVIDLG PGGGDAGGRI VAVGPPAEVA RTEGSRTAPY LAARLARAR
//
