ID   A0A1I4HB07_9RHOB        Unreviewed;       274 AA.
AC   A0A1I4HB07;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE            EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN   ORFNames=SAMN04488004_11673 {ECO:0000313|EMBL:SFL38611.1};
OS   Loktanella salsilacus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Loktanella.
OX   NCBI_TaxID=195913 {ECO:0000313|EMBL:SFL38611.1, ECO:0000313|Proteomes:UP000199550};
RN   [1] {ECO:0000313|EMBL:SFL38611.1, ECO:0000313|Proteomes:UP000199550}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16199 {ECO:0000313|EMBL:SFL38611.1,
RC   ECO:0000313|Proteomes:UP000199550};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC         N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC         COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC         Evidence={ECO:0000256|ARBA:ARBA00001279};
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DR   EMBL; FOTF01000016; SFL38611.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4HB07; -.
DR   STRING; 195913.SAMN04488004_11673; -.
DR   Proteomes; UP000199550; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR   PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:SFL38611.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199550};
KW   Transferase {ECO:0000313|EMBL:SFL38611.1}.
FT   DOMAIN          1..235
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
SQ   SEQUENCE   274 AA;  30505 MW;  D268BC9B294B9F35 CRC64;
     MNLAIRGIFA DIRWNPEGTL LKNAFPDERF DFILANPPFN ISDWNGDLLR EDQRWTFGTP
     PVGSANFAWM AHIHHQLSAN GIGGVVMSNG SMTSTQSGEG EIRKSMVLSN AVDAIVALPG
     QLFFGTPIAA CLWILAKDRS NGTANGSKLR DRRNEVLFID ASSMGTLVSG SRKQKELSDD
     EIERVANTYH SWRGEKQVGP YGDIPGFCVS ANVEEIRKND FIMTPGRYVG AHKKTNDSRI
     SKENLNSLFE NLSQQMAESR RIDEEIVRKL GWSQ
//