ID   A0A1I4HH45_9FIRM        Unreviewed;       543 AA.
AC   A0A1I4HH45;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Two-component system, sensor histidine kinase YesM {ECO:0000313|EMBL:SFL41599.1};
GN   ORFNames=SAMN05216390_12615 {ECO:0000313|EMBL:SFL41599.1};
OS   Lachnospiraceae bacterium KH1T2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1855374 {ECO:0000313|EMBL:SFL41599.1, ECO:0000313|Proteomes:UP000198626};
RN   [1] {ECO:0000313|EMBL:SFL41599.1, ECO:0000313|Proteomes:UP000198626}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH1T2 {ECO:0000313|EMBL:SFL41599.1,
RC   ECO:0000313|Proteomes:UP000198626};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOSY01000026; SFL41599.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4HH45; -.
DR   STRING; 1855374.SAMN05216390_12615; -.
DR   Proteomes; UP000198626; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SFL41599.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198626};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        233..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          255..307
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   COILED          466..493
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   543 AA;  63347 MW;  6C549EA852058889 CRC64;
     MQNHVNQIEY DLKNSVREAI SIADYLNRME SLNSFLRKEY KNDSDYYSAY NNFMENETIQ
     YYYTAQSIQC VTICTENETI VNGTYFVNDK DVKDEEWYKN FVASGREYMV CAFFEDGSSG
     DYIQKGRHIV VFRKLNYFGG NDIIMLDLDY SQIQKDVTRI CGRNNCCLCN DDGEIIVSSG
     GIDNADKPFE GEEYIDKKGT LYEKDIEIYG EELKIFMVDK ESSFFSMMKE KKFILLAIYI
     FNLILPSIVL YFIYRSINDR LFAISENIEL IKKDKYAQII IPPSKDELGE IIQSYNLMVS
     RIRELIETVF KNKEREQELI IAKKQAELHA LQSQINPHFL FNALESIRMH SLIKNEGETA
     QVLEDFSVLL RENIHWNSDT VTLEHECRNA QRYLELQKYR FGDRLNFSIR LQDECKNIEI
     PKFCIITFVE NACVHGIEKK MEGGSVSVIV SRDDDLLYFE IMDSGKGMTE KELEELMEKI
     DNADISYIEK TNKSIGIVNT IIRLKQYYGE KLLVDINSSI DEGTEICIVV HYGETEQNEG
     YDR
//