ID   A0A1I4I014_9RHOB        Unreviewed;      1131 AA.
AC   A0A1I4I014;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SFL47758.1};
GN   ORFNames=SAMN04488042_101354 {ECO:0000313|EMBL:SFL47758.1};
OS   Shimia aestuarii.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae.
OX   NCBI_TaxID=254406 {ECO:0000313|EMBL:SFL47758.1, ECO:0000313|Proteomes:UP000199144};
RN   [1] {ECO:0000313|EMBL:SFL47758.1, ECO:0000313|Proteomes:UP000199144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15283 {ECO:0000313|EMBL:SFL47758.1,
RC   ECO:0000313|Proteomes:UP000199144};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOTQ01000001; SFL47758.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4I014; -.
DR   STRING; 254406.SAMN04488042_101354; -.
DR   OrthoDB; 174266at2; -.
DR   Proteomes; UP000199144; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199144};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        522..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        877..896
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        903..921
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        927..953
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        974..993
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1005..1029
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1050..1074
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1094..1120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1131 AA;  122761 MW;  6F28769D2ADC700F CRC64;
     MRELGDRAGG ILSYFTRHAT AANLLLVVLI IAGLAAFPRM RAQFFPDVIV DNVTVNVTWD
     GAGAEDVDAA IVQVLEPAML AVEGVEQTNS RSTEGRARIT LDFEPGWDMA RATDDVQVAV
     DAVTTLPEEA EEPVVRRGRW RDRVTDVVIT GPVAIDQIAR FADEFIARLY SEGVTRTTIR
     GLAERETIVE ISSVALITHD VSIAQIAEAI KAEVNADPAG DVTGAVARVR TGVEKRAPDE
     IAGIILRSNP DGTKLTIGDV ALIRVEGVNR NRSYFVGEDP AISIRIDRSD KGDAIGIQAT
     VEDVARTMQA TLPKGVEIQL IRTRAEAITG RLNILLDNGA MGLVLVVCLL FLFLNARTAI
     WVAAGIPTAM LAAVALMYVG GLTINMISLF ALIITLGIVV DDAIVVGEHA DARARRLNET
     PVVAAENAAR RMAMPVFSST LTTIIAFFGL TMISGRFGDL IADIPFTVIA VLAASLIECF
     LILPNHMAHA LKHTAKEHWY DVPSRVVNRG FRWFRDVVFR RAIRLVVVMR YPVVAGAILI
     LATQAVLFIQ GDVQWRFFNA PERGSVTGNF AMLPSASRED SLAMMREMQR ATEELGKEYE
     ERYGRNPLDY VLAEVGGNSG RPIPGSDTMD ADLLGGIAIE LIDADLRPYS SFAFVGELQD
     RVARHPLVET VSFRGWRSGP GGDALDVQFF GADSDTLKAA SEALKTALAE FPEVSAVEDS
     LNYDKQELIL ELTPQGHALG FSIDSLGRVL RHRLNGLEAA TYPDGPRSAR IRVQLPEGEL
     TADFLEGSLM RTPQGKYVPL ADLVTVESRT GFSTVRRENG VRQIKVTGDI SEDDPARAEL
     IIERLQEDIL PRIASEQQVE WQLAGLSEQE DNFLSDARTG LILCLTGIYL VLAWVFSSWT
     RPVVVMAIIP FGLVGTIYGH YMHEVPLSMF TVVGLIGMTG IIINDSIVLV TTIDDYAHDR
     GLIPSIIDGT ADRLRPVFLT TATTVLGLAP LLFERSQQAQ FLKPTVITLV YGLGFGMVLV
     LIVVPALLAM QADVSRQVAA LRRGVRARGL RGLLLGTGAV LVVWLGLTLG WTLWQGGMHP
     QLEALVPALE AVQGPGLTVV VFAVGAWGIT MLGYGIGLLG QLFSRRRAAR G
//