ID   A0A1I4I4N1_9PORP        Unreviewed;       347 AA.
AC   A0A1I4I4N1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Sialic acid synthase {ECO:0000313|EMBL:SFL48791.1};
GN   ORFNames=SAMN05216357_1253 {ECO:0000313|EMBL:SFL48791.1};
OS   Porphyromonadaceae bacterium KH3CP3RA.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae.
OX   NCBI_TaxID=1855396 {ECO:0000313|EMBL:SFL48791.1, ECO:0000313|Proteomes:UP000198708};
RN   [1] {ECO:0000313|EMBL:SFL48791.1, ECO:0000313|Proteomes:UP000198708}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH3CP3RA {ECO:0000313|EMBL:SFL48791.1,
RC   ECO:0000313|Proteomes:UP000198708};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOSU01000025; SFL48791.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4I4N1; -.
DR   Proteomes; UP000198708; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
FT   DOMAIN          291..347
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   347 AA;  38981 MW;  1828E6D3E6520FE2 CRC64;
     MNPHTYIIGE IGQNHNGSVD IAKLIVDLVS RPVKEEVFDI DLKPMDAVKL TKRDLKEELS
     VSQMNQPYNS PHAFGRTYGE HRAFLELSDE EHHEIYQHAR SRGLEFVETL CAIGCLSLLK
     LFTPDYLKVA SRDLTNLPLL EAMAETKIPI ILSTGMTGKK ELDDALDIIT RYHSSISILH
     CVSQYPTHPD KLNLNTIRYL KKHYGQYRIG FSDHTIGIAA AAVAVGMGAE IIEKHVSIDR
     RMKGTDQAGS LGPDGVNRMI RDIRVTERWL GKEDLFVEEE VAEARRKLER SLAAKRDLLP
     GDVISESDLH LLSPGDGYQW ADRGLVIGRT VTKKIPKDEI IYGDFLG
//