ID A0A1I4K0L7_9MICO Unreviewed; 473 AA.
AC A0A1I4K0L7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Na+/melibiose symporter {ECO:0000313|EMBL:SFL72117.1};
GN ORFNames=SAMN04515692_110113 {ECO:0000313|EMBL:SFL72117.1};
OS Leifsonia sp. CL147.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leifsonia.
OX NCBI_TaxID=1798215 {ECO:0000313|EMBL:SFL72117.1, ECO:0000313|Proteomes:UP000198997};
RN [1] {ECO:0000313|Proteomes:UP000198997}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL147 {ECO:0000313|Proteomes:UP000198997};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; FOTM01000010; SFL72117.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4K0L7; -.
DR OrthoDB; 7584869at2; -.
DR Proteomes; UP000198997; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23528; -; 1.
DR PANTHER; PTHR23528:SF1; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03092; BT1; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198997};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..473
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 473 AA; 49779 MW; 96D22BEE77C1CDA4 CRC64;
MTNASPEAAP KTASNAVQYQ VKTGAMRRYI TFYSLASLGI ALLWGSLLAI LVPLQVQGIE
FHRIFTGADA GVDLQALTTL QSKVAAGSVT PNADQHRLLG LLSEFNSSRA TSLSIVSSVG
VLLGMLLAPI IGLLSDRTKS RWGRRAPWIA AGGIGGTALI CLMPVAPTIA VMVVIWSLLQ
VLVGVAQGPL TATVADRVPE ARIGVVSGIS GLASYFGAII GAVAAGSLFA SIGLAAYFPI
GILLLLTTMA FVLFARDNTS REMITKPLRF TSVVKSYGVA LGDADYRWAW ISKVLLYLGY
GISSVYSLYM LQSYISPALS ATQAAQTAPL LQFAALPTTL LAMFISGRWS DKIKRRKPFV
VAAGLLMAGS FLIPFVSPTL PAMFLQVMVT GLGYGTFVVV DQALFIDVLP DKEAAGRDLG
LSSLGQNLGN ALGPIVAGAV VGIFAGAYAP VWPIAFVLVT IASLLVLRVK RVR
//
