ID A0A1I4LA93_9RHOB Unreviewed; 613 AA.
AC A0A1I4LA93;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
DE Flags: Fragment;
GN ORFNames=SAMN04488042_1021 {ECO:0000313|EMBL:SFL87851.1};
OS Shimia aestuarii.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae.
OX NCBI_TaxID=254406 {ECO:0000313|EMBL:SFL87851.1, ECO:0000313|Proteomes:UP000199144};
RN [1] {ECO:0000313|EMBL:SFL87851.1, ECO:0000313|Proteomes:UP000199144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15283 {ECO:0000313|EMBL:SFL87851.1,
RC ECO:0000313|Proteomes:UP000199144};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOTQ01000002; SFL87851.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4LA93; -.
DR STRING; 254406.SAMN04488042_1021; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000199144; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR HAMAP; MF_01123; Ac_CoA_synth; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199144}.
FT DOMAIN 1..44
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 46..433
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 495..573
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:SFL87851.1"
SQ SEQUENCE 613 AA; 67822 MW; 9FB7F6E17F3DE6EE CRC64;
FWAEHGKRID WIKPFTKVKS TSFAPGEIDI KWFEDGTLNV SANCIDRHLE TRADQTAIIF
EPDDPNEAAQ HITYKQLHTR VCRFANILEE LGVRKGDRVV IYLPMIPEAA YAMLACARIG
AIHSIVFAGF SPDALAARIN GCDAKVVITA DTAPRGGRKT ALKSNADAAL LHCKDSVKCL
VVKRTGDQTT WIADRDFDYN EMALEANDYC KPAEMSAEDP LFILYTSGST GQPKGVVHCS
GGYLVYAAMT HQYTFDYHEG DIFWCTADVG WVTGHSYIVY GPLANGATTV MFEGVPTYPD
ASRFWQVCEK HKVNQFYTAP TAIRALMGQG NEFVEKCDLS DLRILGTVGE PINPEAWNWY
NDVVGKGRCP IVDTWWQTET GGHMMTPLPG AHATKPGSAM KPFFGVHPVV LDPQSGERIE
GNGVEGVLCI ADSWPGQMRT VWGDHERFEK TYFSDYKGYY FAGDGCRRDA DGDYWITGRV
DDVINVSGHR MGTAEVESAL VAHAAVAEAA VVGYPHDIKG QGIYCYVTLM NDVEPSDELM
KELRTWVRTE IGPIASPDLI QWAPGLPKTR SGKIMRRILR KIAENDYGAL GDTSTLADPS
VVDDLIENRM NKG
//
