ID A0A1I4MNI6_9BACI Unreviewed; 628 AA.
AC A0A1I4MNI6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Sodium/proton antiporter, CPA1 family (TC 2.A.36) {ECO:0000313|EMBL:SFM04597.1};
GN ORFNames=SAMN04488054_11293 {ECO:0000313|EMBL:SFM04597.1};
OS Salibacterium qingdaonense.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae.
OX NCBI_TaxID=266892 {ECO:0000313|EMBL:SFM04597.1, ECO:0000313|Proteomes:UP000199668};
RN [1] {ECO:0000313|EMBL:SFM04597.1, ECO:0000313|Proteomes:UP000199668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6134 {ECO:0000313|EMBL:SFM04597.1,
RC ECO:0000313|Proteomes:UP000199668};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOTY01000012; SFM04597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4MNI6; -.
DR STRING; 266892.SAMN04488054_11293; -.
DR Proteomes; UP000199668; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199668};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 418..500
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 628 AA; 69069 MW; D9FABD3EA3D6D4C8 CRC64;
MEALFACHTK EREEPDMFDS ILSHLMLIGV LGIGSQWFAW RFRMPAIVVM SVAGLLVGPI
FGVMTPSEDF GTLFNPIISV AVAIILFEGS LNLDYREIRG LGKSVYRIIT LGAFLAWILG
SLTAYFVADL SWAVSFVIGG LFIVTGPTVI LPLLRQAKLK ARPAAILKWE GVVVDPLGAL
LAVFAFEIIQ FLTVDSVTAG ALLLFFLASL FAIAIGWACG RGIGWMFETG FVPEFLKSPI
VFTVVIACFA LADEVMHETG LLAVTAMGMT MANMHIASLS DMRHFKENIS VLLLSGIFIM
ITASLDRDTL LQVFDPRILT YVLLMLIVVR PLSIWLSTIN TELSFKEKAL VGWIAPRGIV
ALTVAGYFAN VLEQAGYPGA SIVTPLTFAL VFATVCAHGF SIGALARKLG LSLEGKPGVI
IVGGSSFTTA LAKTLKSMNI PVLITDTSFE QLFNARAEGV PYYRGEILSE QTEYYLDLTP
YEKLIAATDK DSYNSLVCTT FVPDIGRNDI FQLSWHDPDK EHPDDLVLRI GGRILFEKGA
TYAELNRKIE QGYYFVQTRL SKQYTYKTFL KDIQPDTLPI LNFKPTGKFD FFTSEAPLKP
EAGDTIICMV PPVRLIESGE MSPEQSDE
//
