ID   A0A1I4MPK8_9PROT        Unreviewed;       346 AA.
AC   A0A1I4MPK8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=O-acetyl-ADP-ribose deacetylase (Regulator of RNase III), contains Macro domain {ECO:0000313|EMBL:SFM04977.1};
GN   ORFNames=SAMN05421880_10527 {ECO:0000313|EMBL:SFM04977.1};
OS   Nitrosomonas nitrosa.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=52442 {ECO:0000313|EMBL:SFM04977.1, ECO:0000313|Proteomes:UP000199561};
RN   [1] {ECO:0000313|EMBL:SFM04977.1, ECO:0000313|Proteomes:UP000199561}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm146 {ECO:0000313|EMBL:SFM04977.1,
RC   ECO:0000313|Proteomes:UP000199561};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O = a
CC         thymidine in DNA + ADP-D-ribose; Xref=Rhea:RHEA:71655, Rhea:RHEA-
CC         COMP:13556, Rhea:RHEA-COMP:18051, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:57967, ChEBI:CHEBI:137386, ChEBI:CHEBI:191199;
CC         Evidence={ECO:0000256|ARBA:ARBA00035885};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:71656;
CC         Evidence={ECO:0000256|ARBA:ARBA00035885};
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DR   EMBL; FOUF01000005; SFM04977.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4MPK8; -.
DR   STRING; 52442.SAMN05421880_10527; -.
DR   Proteomes; UP000199561; Unassembled WGS sequence.
DR   CDD; cd02901; Macro_Poa1p-like; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   PANTHER; PTHR12521:SF0; ADP-RIBOSE GLYCOHYDROLASE OARD1; 1.
DR   PANTHER; PTHR12521; PROTEIN C6ORF130; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SUPFAM; SSF52949; Macro domain-like; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199561}.
FT   DOMAIN          1..163
FT                   /note="Macro"
FT                   /evidence="ECO:0000259|PROSITE:PS51154"
SQ   SEQUENCE   346 AA;  38961 MW;  9CB4DDEF33846795 CRC64;
     MIKFTRGDIL QADVEAIVNT VNCVGVMGRG IALQFKKAWP KNFKAYAAAC KKNEVQPGRL
     FVFATQQRAN PRYIINFPTK RHWRDASRME DIDSGLEALA AAIREKHIQS IAIPPLGCGL
     GGLDWNQVKQ KIEQSLSALP DVYVLIYEPQ GAPENDRVAH TPTAPKMTAG RAVLIELLQR
     YLAGLLDPTI SLLEVHKLLY FMQEAGQPLR LKYQKAYYGP YAENLRHVLN AIEGHFISGY
     ADGGDAPDKP LQLLPGAIEE ANAFLEKHPQ SRERFNKVSQ LVEGFESPFG LELLSTVHWL
     CKYEQAATIE DVITATHTWN QHKRQFTPRQ IELALAVLNR YHWLPA
//