ID   A0A1I4NNJ5_9EURY        Unreviewed;       263 AA.
AC   A0A1I4NNJ5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:SFM17104.1};
GN   ORFNames=SAMN04488696_0174 {ECO:0000313|EMBL:SFM17104.1};
OS   Methanolobus profundi.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX   NCBI_TaxID=487685 {ECO:0000313|EMBL:SFM17104.1, ECO:0000313|Proteomes:UP000198535};
RN   [1] {ECO:0000313|EMBL:SFM17104.1, ECO:0000313|Proteomes:UP000198535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mob M {ECO:0000313|EMBL:SFM17104.1,
RC   ECO:0000313|Proteomes:UP000198535};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOUJ01000001; SFM17104.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4NNJ5; -.
DR   STRING; 487685.SAMN04488696_0174; -.
DR   OrthoDB; 15395at2157; -.
DR   Proteomes; UP000198535; Unassembled WGS sequence.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR   GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR   CDD; cd06578; HemD; 1.
DR   Gene3D; 3.40.50.10090; -; 2.
DR   InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR   InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR   InterPro; IPR039793; UROS/Hem4.
DR   PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR   PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR   Pfam; PF02602; HEM4; 1.
DR   SUPFAM; SSF69618; HemD-like; 1.
PE   4: Predicted;
FT   DOMAIN          23..255
FT                   /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT                   synthase"
FT                   /evidence="ECO:0000259|Pfam:PF02602"
SQ   SEQUENCE   263 AA;  28958 MW;  81C0FB29C9642CD5 CRC64;
     MAEDIKKPVL AIMRPKRYLE DSVALAEKMG FEPLAVPMIE LADMKDEYFD GFVEHVMSGV
     SDYVIFTSAN GIDFTLSKIE DREGFIDALN ATKVIAIGPT TRKALEDLGI NVLGMPGVYS
     SEGLVEFLCP DVKGKVIDTA RSFYGSTLLI EGLKECGAEV HETKVYTLTK PEGSAQEDFI
     SRVLAREIDV FAFTSSMMVR NFFEHAVDQS SKKDVIDIMN DSIVAAIGIP TGQTIESYGV
     NVSVTPGKFT FEDILKKVRE LLD
//