ID   A0A1I4QU67_9BACI        Unreviewed;       883 AA.
AC   A0A1I4QU67;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Putative drug exporter of the RND superfamily {ECO:0000313|EMBL:SFM43561.1};
GN   ORFNames=SAMN04488054_1509 {ECO:0000313|EMBL:SFM43561.1};
OS   Salibacterium qingdaonense.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae.
OX   NCBI_TaxID=266892 {ECO:0000313|EMBL:SFM43561.1, ECO:0000313|Proteomes:UP000199668};
RN   [1] {ECO:0000313|EMBL:SFM43561.1, ECO:0000313|Proteomes:UP000199668}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.6134 {ECO:0000313|EMBL:SFM43561.1,
RC   ECO:0000313|Proteomes:UP000199668};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR   EMBL; FOTY01000050; SFM43561.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4QU67; -.
DR   STRING; 266892.SAMN04488054_1509; -.
DR   OrthoDB; 9782006at2; -.
DR   Proteomes; UP000199668; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199668};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        176..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        713..732
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        739..761
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        773..794
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        815..834
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        846..870
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          200..329
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          737..870
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   883 AA;  95212 MW;  1E08052173A7E0F5 CRC64;
     MRTILRFRWV IASALLAVTV LLFFLTPDLS RLAGEEESFQ LPEDMTSQQA DTILEDAGEG
     AESISLVLEL DNWLTAEKEQ NITGYLEDIR SADDNIEEVT SPFEREEVRN QLVSEENNVV
     LVPVSVNGGQ EAAVQAGEAL QSLSVPDGMT QYVTGDAIIS DAVDETTQDG LQRTEGITVV
     LIFALLLVVF RAVVTPFVPL ISVAVTYLLS QSIISLLAEG FGFPLSTYTQ IFLVAVLFGI
     GTDYCILLLS RYKEELSDGQ EVKDAIVNTY STAGKTLLYS GIAVFVGFAA IGFADFAIFQ
     SAVGVAVGIA VLLLVLYTLM PFFMAVLKDK LFWPSKKGGE HQDNKLWKAM GRLSVFRPVI
     SIVIAAVVTL PFLLTYDNDI SYNNTDEIGS EAQSVEGLHV IESAFGMGDA LPLEMVIDSE
     NDMITKEKLA AVESLARTLE QSSAVDEVRG VTRPTGSVLD DMYVDNQLED VSTGISDARD
     GLGEVQNGLS EVRNGLQDMN SQVQGSASGS RGSLNEAVSG IQDINSQVGT ISSQLQQTGN
     TQAAVQQLSG VQQGLTEVQN GLQQGSQQMS NQQQAQANDL AASLDELTNG VQEAINGLED
     IESGLESAQT YTAEASGASY IRGSGVFVPD DLLENEDFQE GVRQYAFEDQ TGMTIEVSLK
     EDPYSVEAIE AVDQVKQLVS METAGTPLEQ DTITYSGVPG TNADLEDIST EDFTNTIIII
     LIGLFLILAV LLRSLVKPVF ILGGLMLAYY TAMGAAEMIF VQGLDYPGMM WPVPFFGFVM
     LVALGVDYSI FLFDRYREEA ELGVQEGLLK AMKKMGTVII TAAIILSGTF GAMIPSGVLT
     LMQVGTVVVT GLLLFGLIIL PLFIPAVVSL HDSPPSLSKR KEK
//