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Database: UniProt
Entry: A0A1I4RA88_ECTMO
LinkDB: A0A1I4RA88_ECTMO
Original site: A0A1I4RA88_ECTMO 
ID   A0A1I4RA88_ECTMO        Unreviewed;       355 AA.
AC   A0A1I4RA88;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   08-MAY-2019, entry version 7.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=SAMN05421721_10733 {ECO:0000313|EMBL:SFM49119.1};
OS   Ectothiorhodospira mobilis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Ectothiorhodospira.
OX   NCBI_TaxID=195064 {ECO:0000313|EMBL:SFM49119.1, ECO:0000313|Proteomes:UP000199556};
RN   [1] {ECO:0000313|EMBL:SFM49119.1, ECO:0000313|Proteomes:UP000199556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4180 {ECO:0000313|EMBL:SFM49119.1,
RC   ECO:0000313|Proteomes:UP000199556};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; FOUO01000007; SFM49119.1; -; Genomic_DNA.
DR   BioCyc; GCF_900114895:BM214_RS06965-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000199556; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000199556};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199556};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       44    335       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   355 AA;  38133 MW;  2BC112E8C39E2341 CRC64;
     MPYPTDDLRI VNIREALPPR RLLEDLPITE AAARTVFETR RALQAILRGE DDRLVVIAGP
     CSIHDVEAAR DYARHLAAAR DALAGDLLVI MRVYFEKPRT IVGWKGLIND PGLDGSFEIN
     KGLHLARGLL LHLADSGMPG ATEYLDPISP QYISDLVAWG AIGARTTESQ VHRELASGLS
     CPVGFKNSTD GSLQIAIDAI RSAGKPHHFL SVTKAGHSAI FSTAGNPDGH IILRGGRRPN
     YDAASIQEAA SALEDAGLPA RLMVDCSHAN SRKDPARQAQ VARDVAAQVG AGDRRIMGMM
     LESHLVAGRQ DVTPGRPLTY GQSITDACMG WDDTLPVLQE LAAGVRSRRA AAGRD
//
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