ID A0A1I4RQ48_9PROT Unreviewed; 91 AA.
AC A0A1I4RQ48;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=4a-hydroxytetrahydrobiopterin dehydratase {ECO:0000256|ARBA:ARBA00013252};
DE EC=4.2.1.96 {ECO:0000256|ARBA:ARBA00013252};
GN ORFNames=NMYAN_120020 {ECO:0000313|EMBL:CAE6492551.1},
GN SAMN05421880_12029 {ECO:0000313|EMBL:SFM54100.1};
OS Nitrosomonas nitrosa.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=52442 {ECO:0000313|EMBL:SFM54100.1, ECO:0000313|Proteomes:UP000199561};
RN [1] {ECO:0000313|EMBL:SFM54100.1, ECO:0000313|Proteomes:UP000199561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm146 {ECO:0000313|EMBL:SFM54100.1,
RC ECO:0000313|Proteomes:UP000199561};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAE6492551.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nitrosomonas nitrosa 18-3D {ECO:0000313|EMBL:CAE6492551.1};
RA Han P.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin =
CC (6R)-L-erythro-6,7-dihydrobiopterin + H2O; Xref=Rhea:RHEA:11920,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15642, ChEBI:CHEBI:43120; EC=4.2.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00001554};
CC -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine dehydratase
CC family. {ECO:0000256|ARBA:ARBA00006472}.
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DR EMBL; CAJNAP010000004; CAE6492551.1; -; Genomic_DNA.
DR EMBL; FOUF01000020; SFM54100.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4RQ48; -.
DR STRING; 52442.SAMN05421880_12029; -.
DR OrthoDB; 5297462at2; -.
DR Proteomes; UP000199561; Unassembled WGS sequence.
DR Proteomes; UP000601736; Unassembled WGS sequence.
DR GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR Gene3D; 3.30.1360.20; Transcriptional coactivator/pterin dehydratase; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR036428; PCD_sf.
DR InterPro; IPR001533; Pterin_deHydtase.
DR Pfam; PF01329; Pterin_4a; 1.
DR SUPFAM; SSF55248; PCD-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CAE6492551.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199561}.
SQ SEQUENCE 91 AA; 10190 MW; F395BF646D464EF7 CRC64;
MNVAKLPDGW ESRGKPPTLF RRFVFGRYNE TRDFLDALAA LTDEAGLHPQ NINFASTYVN
ITLDANDSGE LGEAELSLAT RINQLYLKKS D
//
