ID A0A1I4RQN3_9PROT Unreviewed; 431 AA.
AC A0A1I4RQN3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=NMYAN_120035 {ECO:0000313|EMBL:CAE6492650.1},
GN SAMN05421880_12041 {ECO:0000313|EMBL:SFM54459.1};
OS Nitrosomonas nitrosa.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=52442 {ECO:0000313|EMBL:SFM54459.1, ECO:0000313|Proteomes:UP000199561};
RN [1] {ECO:0000313|EMBL:SFM54459.1, ECO:0000313|Proteomes:UP000199561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm146 {ECO:0000313|EMBL:SFM54459.1,
RC ECO:0000313|Proteomes:UP000199561};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAE6492650.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nitrosomonas nitrosa 18-3D {ECO:0000313|EMBL:CAE6492650.1};
RA Han P.;
RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CAJNAP010000004; CAE6492650.1; -; Genomic_DNA.
DR EMBL; FOUF01000020; SFM54459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4RQN3; -.
DR STRING; 52442.SAMN05421880_12041; -.
DR OrthoDB; 9121563at2; -.
DR Proteomes; UP000199561; Unassembled WGS sequence.
DR Proteomes; UP000601736; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SFM54459.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199561};
KW Transferase {ECO:0000313|EMBL:SFM54459.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..431
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 431 AA; 48973 MW; 27137C1829B54113 CRC64;
MFKIKYGIRL RVTLALAIFC IIIVGALAIS LYFASDDIEE THIEQIMKAE MNHVIHHYLQ
HTRFTPQVGS SLKSYVIRNT EEESQLPDYL QNLDRGSHKI FRHDQEIRVL VQYAGGVKFV
VAYKIGLHEQ RQREFRLLVV LSLVAVVAIA FLIGYLLAGL LVKQVTDLAE RVKRLLPIND
STGLVSNNIH CVSLSQPGQD EEVAQLARTL EDYQYRIVRM LQREQEFTSN ISHELRTPIT
TILTSCELLL AEQNLSPKAY ARIRNIEAVS NRMSEQVQAL LFLAREQALG TMEPVAIAEC
VYDAVEPFCE EIYQKNLELD VTVKPGVVLT LNRQALHTAL VNILRNAVQY TEQGFIRISF
DNNRLSIADS GIGIEPAFMP FLYERFFRGS EKTQGLGIGL VIVKRICDYY DWRIEVDSTP
GSGATFHIVF P
//
