ID   A0A1I4T4A6_9PSEU        Unreviewed;       159 AA.
AC   A0A1I4T4A6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=O-acetyl-ADP-ribose deacetylase (Regulator of RNase III), contains Macro domain {ECO:0000313|EMBL:SFM71471.1};
GN   ORFNames=SAMN05421805_1011272 {ECO:0000313|EMBL:SFM71471.1};
OS   Saccharopolyspora antimicrobica.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=455193 {ECO:0000313|EMBL:SFM71471.1, ECO:0000313|Proteomes:UP000199398};
RN   [1] {ECO:0000313|EMBL:SFM71471.1, ECO:0000313|Proteomes:UP000199398}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CPCC 201259 {ECO:0000313|EMBL:SFM71471.1,
RC   ECO:0000313|Proteomes:UP000199398};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O = a
CC         thymidine in DNA + ADP-D-ribose; Xref=Rhea:RHEA:71655, Rhea:RHEA-
CC         COMP:13556, Rhea:RHEA-COMP:18051, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:57967, ChEBI:CHEBI:137386, ChEBI:CHEBI:191199;
CC         Evidence={ECO:0000256|ARBA:ARBA00035885};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:71656;
CC         Evidence={ECO:0000256|ARBA:ARBA00035885};
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DR   EMBL; FOUP01000001; SFM71471.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4T4A6; -.
DR   STRING; 455193.SAMN05421805_1011272; -.
DR   OrthoDB; 9780211at2; -.
DR   Proteomes; UP000199398; Unassembled WGS sequence.
DR   CDD; cd02901; Macro_Poa1p-like; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   PANTHER; PTHR12521:SF0; ADP-RIBOSE GLYCOHYDROLASE OARD1; 1.
DR   PANTHER; PTHR12521; PROTEIN C6ORF130; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SUPFAM; SSF52949; Macro domain-like; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   4: Predicted;
FT   DOMAIN          1..159
FT                   /note="Macro"
FT                   /evidence="ECO:0000259|PROSITE:PS51154"
SQ   SEQUENCE   159 AA;  17243 MW;  3F3A8B87F454BE34 CRC64;
     MAGIDYVRGD ATAPQGKGVK VIAHVCNDLG GWGKGFVVAI SRRWPEPEQE YRRWHRERAG
     NDFALGAVQF VQAGQWIWVA NMVGQRGMRR GSKGVPVRYE AIDAALGSVA DKALELGASV
     HMPRIGCGLA GGEWPQVEPL IQDRLVARGV PVTVYDHAA
//