ID   A0A1I4TUP1_9ACTN        Unreviewed;       773 AA.
AC   A0A1I4TUP1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=ATP-dependent exoDNAse (Exonuclease V), alpha subunit, helicase superfamily I {ECO:0000313|EMBL:SFM80496.1};
GN   ORFNames=SAMN04487980_1005317 {ECO:0000313|EMBL:SFM80496.1};
OS   Streptomyces sp. cf124.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761903 {ECO:0000313|EMBL:SFM80496.1, ECO:0000313|Proteomes:UP000198530};
RN   [1] {ECO:0000313|EMBL:SFM80496.1, ECO:0000313|Proteomes:UP000198530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF124 {ECO:0000313|EMBL:SFM80496.1,
RC   ECO:0000313|Proteomes:UP000198530};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOUV01000005; SFM80496.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4TUP1; -.
DR   Proteomes; UP000198530; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029493; RecD-like_HHH.
DR   Pfam; PF14490; HHH_4; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:SFM80496.1};
KW   Exonuclease {ECO:0000313|EMBL:SFM80496.1};
KW   Helicase {ECO:0000313|EMBL:SFM80496.1};
KW   Hydrolase {ECO:0000313|EMBL:SFM80496.1};
KW   Nuclease {ECO:0000313|EMBL:SFM80496.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:SFM80496.1}.
FT   DOMAIN          170..257
FT                   /note="RecD helicase-like helix-hairpin-helix"
FT                   /evidence="ECO:0000259|Pfam:PF14490"
FT   REGION          1..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..103
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   773 AA;  78839 MW;  FB9D8BA390AAD352 CRC64;
     MSTEPSTTGT DEPGGRGDAT ASEAPDDATA GGTPEGSADD AGTAETAETP ETASEAASEA
     VPETASGAAS ETAAEVSEAQ AELAAQRLER ERIEKRKAEK KTPVTSGTKL SGTAADLLAA
     VRAVEGGRKP TATVFDEPEP APRRPAQEPA RRPRPVAPPA GAAAPSGETV EAVRAVLAEG
     GAPEALVPQV AEALGEGAGA RLREDPWQLL RVPGVRPEQA DGFARALLGT ECRPDDERRG
     RAVTVWLLEQ AAVAGHTALE APALIAALGQ RSVPDPDEAV QSTVAEGEAL VFQDALDDAP
     STPRSAPAPT PASANAGSGS EGDGEDDEAE EERPVRVLIG LERYALAEES LADGLARVMN
     SLPKDGPTDW APAAASAPRS TAELIRAVAG HSLVLHTGGE AARAEPAALV TAARTLGLRA
     YAATHSADGR RRFAAQLSSA DAEPAEGAGT VEGAESVVTT LAGLLSGAEG PGRDAEGALV
     LDLLVVLDAP QVDVETAALL AESLPDGSRL VLSGDPGVLW SAGPGRVFAD LLAARACPQV
     ASRTPDPGPI GELVSGIGIG ELNQVDAPGK EVVIVPVRDA GEAVHRTAQL VVDSVPRAFG
     IPAEQVQVIT PGHGGAAGTR ALNASLKERL NPGPGRFGGF DPGDRVAHSP APGRTTPGRV
     VKADAEGLHL ECAGTAVVVP KERVEQTVRH GWALTAHQAV GHRWPAAVVV LPGDAAQALT
     RPWVYTAFGR AERHLSVVHG VEQALPRAVA EVPPKPRTTR LPALLKAQVP SAD
//