ID A0A1I4VAW4_9GAMM Unreviewed; 1117 AA.
AC A0A1I4VAW4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216289_101264 {ECO:0000313|EMBL:SFM98130.1};
OS Dokdonella immobilis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Dokdonella.
OX NCBI_TaxID=578942 {ECO:0000313|EMBL:SFM98130.1, ECO:0000313|Proteomes:UP000198575};
RN [1] {ECO:0000313|EMBL:SFM98130.1, ECO:0000313|Proteomes:UP000198575}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7659 {ECO:0000313|EMBL:SFM98130.1,
RC ECO:0000313|Proteomes:UP000198575};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000256|ARBA:ARBA00006434}.
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DR EMBL; FOVF01000001; SFM98130.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4VAW4; -.
DR STRING; 578942.SAMN05216289_101264; -.
DR OrthoDB; 9764438at2; -.
DR Proteomes; UP000198575; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; NF041832; near_NosP_CTERM; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF9; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000198575};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 599..639
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 764..973
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 993..1107
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 730..757
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1042
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1117 AA; 120129 MW; 5815EB4A68F7D473 CRC64;
MLPDLKILGA GLLWLGLLFG AAVLGDRRPK FFARHWALIY SLSLAVYCTS WTFYGTVTQA
SRSGWWLPPT FVGTILIYLF GFGLLMRLVS IARAHNSSSL ADLVAIRLGR SPAIAALVTA
VAVIGIVPYI ALQLKSVAMS YGMLARRQDL MAPAWQDSAL WVALAMALFA MLFGARRASA
TAHNRGLVLA MAFESLFKLI AMLALGVLVW FGISLPADAS PSLPPPGGSA GFTTLIMLGA
FAVFTLPHQF HAGVVECRDP EHVRTARWLF PLYMLLIALP ILPLARAGDA LLAPLGVPSD
LYVLALPLAN GHGTLALIAF LGGLSAATSM VVVATLALSL MIGNHWIAPL RVRAGWGRAA
VGDLRGEVLL QRRLIILVVV LLAWAYSRVL VASDALADIG AVSFSALSAI APGVLVAVYR
PQLGARAVGA GLVAGSLVWL YALMLPVLAG GSLAWVEQGP FGIEWLAPDR LLGFDDWSRL
ARAVVLSLAA NVAVIGLVAS SRFAHGAKSG HRGLVDVGDL RALASRFLAD EQVEALFGAN
EGDSPASETL VAAIEHELAA VIGASSARLL LTVARRERSV ELEAVAAIVG ETSQDLRFNQ
RVLEAALENM SQGISVVDRD LGLVAWNQPY ARLFGYPPEL LRVGVPIADL LRWNLTHRLS
VAHSADEEVH KRIRHMRAGT PYVAERTFET DDGERVVEIR GNPMPGGGFV ATFTDVTEFR
RNEAELMQVA ETLELRVEER TAELDMARRE AEKANRAKSR FLAAVSHDLA QPLNAAHLFT
HALAQRLGHA EYREAVDNIS GALTSAEDLL SGLLDISRLD GGQTRARAEA FPLREWLGGL
AAEFSVLADE RGLRLDAVPC SAWIRSDPQL LRRIVQNFLA NAVRHTRSGR ILLGCRRRRS
HVSIEVWDTG PGIALADQEL IFEEFRRLGH SGEGLGLGLA IADRIARLLG HRISLRSRPG
RGTVFSIEVP TTATLQPPLT VAPPQAQALP RRRLLVVDND PAVLKAMQAL LAGWQSEVSA
AQTPAQARLL FAEHGADVLL LDYHLDDHVS GLQLRESLGP AAQGIPCVII TADHGKTVSD
AVLAAGCQLL HKPLKPLALR SLLAQLIARD TGGENSR
//
