ID A0A1I4VZ70_9ACTN Unreviewed; 239 AA.
AC A0A1I4VZ70;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=DNA-binding transcriptional regulator, IclR family {ECO:0000313|EMBL:SFN06552.1};
GN ORFNames=SAMN04489713_10192 {ECO:0000313|EMBL:SFN06552.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFN06552.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFN06552.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFN06552.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVH01000001; SFN06552.1; -; Genomic_DNA.
DR RefSeq; WP_021598712.1; NZ_FOVH01000001.1.
DR AlphaFoldDB; A0A1I4VZ70; -.
DR STRING; 1993.SAMN04489713_10192; -.
DR eggNOG; COG1414; Bacteria.
DR InParanoid; A0A1I4VZ70; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF39; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:SFN06552.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000183413};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 7..66
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 67..236
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 239 AA; 24949 MW; F803E3201808BD31 CRC64;
MDNSSGVGVL DKAVLVLNAL EAGPASLAQL VQTTGLARPT AHRLAVALEH HRLVHRDTQG
RFILGPRLAE LAVAAGEDRL LAIAQPILAQ LRDLTGESAS LFRRQGDVRV CVAAAERTSG
LRDTIPVGAA LPMTAGSAAQ VLLAWEEPDR LHRGLRGAKF EATTLASVRR RGWAQSVGER
EQGVGSVSAP VRGAGGRVIA AVSVSGPLER LTRSPGRLHA GPVAAAAEKI SEGMRRTAS
//
