ID A0A1I4WLU2_9FLAO Unreviewed; 929 AA.
AC A0A1I4WLU2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=oxoglutarate dehydrogenase (succinyl-transferring) {ECO:0000256|ARBA:ARBA00012280};
DE EC=1.2.4.2 {ECO:0000256|ARBA:ARBA00012280};
GN ORFNames=SAMN05421738_10762 {ECO:0000313|EMBL:SFN14120.1};
OS Algoriella xinjiangensis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Algoriella.
OX NCBI_TaxID=684065 {ECO:0000313|EMBL:SFN14120.1, ECO:0000313|Proteomes:UP000199149};
RN [1] {ECO:0000313|EMBL:SFN14120.1, ECO:0000313|Proteomes:UP000199149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XJ109 {ECO:0000313|EMBL:SFN14120.1,
RC ECO:0000313|Proteomes:UP000199149};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOUZ01000007; SFN14120.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4WLU2; -.
DR STRING; 684065.SAMN05421738_10762; -.
DR OrthoDB; 9759785at2; -.
DR Proteomes; UP000199149; Unassembled WGS sequence.
DR GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR CDD; cd02016; TPP_E1_OGDC_like; 1.
DR Gene3D; 3.40.50.12470; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.50.11610; Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain; 1.
DR Gene3D; 1.10.287.1150; TPP helical domain; 1.
DR InterPro; IPR032106; 2-oxogl_dehyd_N.
DR InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR031717; KGD_C.
DR InterPro; IPR042179; KGD_C_sf.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR NCBIfam; TIGR00239; 2oxo_dh_E1; 1.
DR PANTHER; PTHR23152:SF4; 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1; 1.
DR PANTHER; PTHR23152; 2-OXOGLUTARATE DEHYDROGENASE; 1.
DR Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR Pfam; PF00676; E1_dh; 1.
DR Pfam; PF16870; OxoGdeHyase_C; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 596..789
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 929 AA; 104295 MW; D8492413D257996D CRC64;
MDRFSFLNAA HIEFIGDLYD QYVQYPDSIE PSWKAFFQGY DFANATYDGE PLFAPAPQSA
SNRGSQAAQA VVNPTVVSQV PENVQKEFKV INLIDAYRTR GHLFTKTNPV RERRKFEPSL
DIKNFGLTDA DLGLTFNAGE ILGIGGPITL REIIGHLENM YCESIGIEYM YVREPQKINW
IQNWLNQNLN QPKLSKEEKE RVLAKLNEAT AFENFMHTKY VGQKRFSVEG NESLIPALDT
LINKSAEHGV EEVIVGMAHR GRLNVLANIF GKSYSQIFSE FEGKAFDSDL MAGDVKYHMG
SSNKIKALNG KDILINLAPN PSHLETVDAV VEGIARAKAE EDYNEDYSKI IPILIHGDAA
VAGQGIVYEV VQMAGLDGYT TGGTVHVVVN NQIGFTTNYL DARTSTYCTD VAKVTLSPVM
HVNSDDVEAV VHAFRFAADY RAQFGSDVFI DLLGYRKYGH NEGDEPKFTQ PKLYNLIAKH
PNPREIYKDK LLKEGVIGEE IVKQKEAEFK ALLEVNFEAS KEIERNHIFP FIPEEWEGFT
IATEEKVLAT ADTAYPADKL KEIAKAVSTV PEGKKLIKKV SRLIEGRGKM IEDDKIDWGL
GEALAYGSIL TDGRNVRLSG EDVERGTFSH RHAVVKTEDT EEEIILLNHI DDNQGKLRIY
NSLLSEYAVL GFDYGYAMAN PKALTIWEAQ FGDFVNGAQI VIDQYITAAE DKWKLQNGLV
MLLPHGYEGQ GAEHSSAKLE RFLQMCAGNN MFVANITTPA NFFHALRRQV VTDYRKPLIV
MSPKSLLRHP AAVSKLEDFS NGAFQEIIDD VTVDAKQVKK VVFCSGKIYY ELDKKRQELG
DKETAIVRLE QLYPLNEEKV DAIISQYGNA ELVWAQEEPE NMGAWSYILR KLRKYPFDVI
SPAESAATAP GSSKRWAAIF EEVINKVFK
//
