ID   A0A1I4XCR9_9PROT        Unreviewed;       213 AA.
AC   A0A1I4XCR9;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Deoxyadenosine/deoxycytidine kinase {ECO:0000313|EMBL:SFN23575.1};
GN   ORFNames=SAMN05216386_0046 {ECO:0000313|EMBL:SFN23575.1};
OS   Nitrosospira briensis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=35799 {ECO:0000313|EMBL:SFN23575.1, ECO:0000313|Proteomes:UP000183107};
RN   [1] {ECO:0000313|Proteomes:UP000183107}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nsp8 {ECO:0000313|Proteomes:UP000183107};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOVJ01000001; SFN23575.1; -; Genomic_DNA.
DR   RefSeq; WP_074793474.1; NZ_FOVY01000003.1.
DR   AlphaFoldDB; A0A1I4XCR9; -.
DR   STRING; 1266925.GCA_000619905_00814; -.
DR   OrthoDB; 9776634at2; -.
DR   Proteomes; UP000183107; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01673; dNK; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002624; DCK/DGK.
DR   InterPro; IPR031314; DNK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10513:SF46; DEOXYGUANOSINE KINASE; 1.
DR   PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR   Pfam; PF01712; dNK; 1.
DR   PIRSF; PIRSF000705; DNK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Kinase {ECO:0000313|EMBL:SFN23575.1};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183107};
KW   Transferase {ECO:0000313|EMBL:SFN23575.1}.
FT   DOMAIN          9..201
FT                   /note="Deoxynucleoside kinase"
FT                   /evidence="ECO:0000259|Pfam:PF01712"
FT   ACT_SITE        87
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT   BINDING         13..21
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT   BINDING         139..143
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT   BINDING         183..185
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
SQ   SEQUENCE   213 AA;  25198 MW;  356B044EB6D3DDA6 CRC64;
     MKLEEYRYIV VEGPIGVGKT SLARRIADHL GSELLLEKPA ENPFLEKFYS DIRRYALPTQ
     LFFLFQRANQ LQGRAQIDMF TKTTVGDFLL DKDPLFARLT LSDAEYDLYW KIYHHLQPKA
     ALPDLVIYLQ APPATLIERV RRRGNPFEKN ISEEYLWRLA DSYTRFFHHY EDARLMIINS
     ENLNFVDSQA DFDLLLRQVE QMRGPREYFN RGI
//