ID   A0A1I4XGK2_9PROT        Unreviewed;       468 AA.
AC   A0A1I4XGK2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=TIR domain-containing protein {ECO:0000313|EMBL:SFN25038.1};
GN   ORFNames=SAMN05216386_0122 {ECO:0000313|EMBL:SFN25038.1};
OS   Nitrosospira briensis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=35799 {ECO:0000313|EMBL:SFN25038.1, ECO:0000313|Proteomes:UP000183107};
RN   [1] {ECO:0000313|Proteomes:UP000183107}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nsp8 {ECO:0000313|Proteomes:UP000183107};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOVJ01000001; SFN25038.1; -; Genomic_DNA.
DR   RefSeq; WP_074793583.1; NZ_FOVJ01000001.1.
DR   AlphaFoldDB; A0A1I4XGK2; -.
DR   OrthoDB; 7055795at2; -.
DR   Proteomes; UP000183107; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000183107}.
FT   DOMAIN          6..130
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   468 AA;  53184 MW;  451DC5C2FDFA9093 CRC64;
     MNRSTIFLSH AAPEDNDFTD WLAAKLTLMG YTVWHDLGRL KGGDLFWSKI EAAIRNDTIR
     FVAIVSEVSY KKDGVRNEWA LAATIEKTIP GFVIPIRLDG FDFNRLPITI HQKNVIDFCC
     GWHHGLTQLL DTLSEANIAN SNSVDPVMAK GWMVQSADDA IVKTDRPETL ESNWLPILSL
     PSTMETAKIL FSSRQIPVTS TNRLLPWFEL GDHIIGFAPG AALVEMFKES VPLRVVTAVD
     TESFVNEGTM WNHQRITVGD ARNRAAYLIR QAWDLAMERT GLRPYELSNH RLIWYVPTGL
     IPKDKVEFIE ASGKRRKKKL CGESEKLNVN WHYAVSMRPV FNSPRRIELG AHIVFTDMDG
     CLVQSVERMH RLRRRFCKNW WNDRWRGFLR AFLALVAQGG DAILLPVGGD RSIRVGAFPL
     TFNALNGLSD VVDLAEDDDV ELDENDDLIE LPEDDAVFID KIQEIHER
//