ID A0A1I4XQP5_9FLAO Unreviewed; 473 AA.
AC A0A1I4XQP5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Hemolysin, contains CBS domains {ECO:0000313|EMBL:SFN28122.1};
GN ORFNames=SAMN05421738_109130 {ECO:0000313|EMBL:SFN28122.1};
OS Algoriella xinjiangensis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Algoriella.
OX NCBI_TaxID=684065 {ECO:0000313|EMBL:SFN28122.1, ECO:0000313|Proteomes:UP000199149};
RN [1] {ECO:0000313|EMBL:SFN28122.1, ECO:0000313|Proteomes:UP000199149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XJ109 {ECO:0000313|EMBL:SFN28122.1,
RC ECO:0000313|Proteomes:UP000199149};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOUZ01000009; SFN28122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I4XQP5; -.
DR STRING; 684065.SAMN05421738_109130; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000199149; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR43099:SF5; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..225
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 246..304
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 309..366
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 473 AA; 53096 MW; 87657A15A6E6C17E CRC64;
MDTYSQISTL FLVANHNVTD EISIAKLLLT IFLVLLNGFF VAAEFAIVKV RSSQIEVNQD
INERTSNVAK LIISHLDSYL AATQLGITLA SLGLGWVGES SLSPVIIKIF EVLGLTSPSW
TLIAQNAAFP IAFVIITILH IVFGELAPKS IAIQYPTKTT FTVAWPLRAF YFVFKPLIMM
MNGLANVILR AFGIHPIHGG EIHSEEELKM IITESSEGGA IEESERNLIQ NVFEFDDRRV
MNIQTLRKNV SAINIKTPVK EALDFAINEG YSRYPVYEEE FDNIKGVIYA KDLIKQLLGN
PNETDISGLL REPIFISENA LIKNVMKQFQ KRHMQIAIVT NEVGEVAGIV SMEDILEELV
GEIQDEYDNE DPIVSRVSEG VYNVNAHNAI SDINRLVPFR FDESEHYDTL AGLISESYPD
RELVEGDLVE LGEYTGTIIK MYRNSVEQVQ LKVKEELIDN YKDEPDSAID DEN
//
