ID A0A1I4Y2D7_9PROT Unreviewed; 415 AA.
AC A0A1I4Y2D7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Integrase {ECO:0000313|EMBL:SFN32216.1};
GN ORFNames=SAMN05216386_0469 {ECO:0000313|EMBL:SFN32216.1};
OS Nitrosospira briensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=35799 {ECO:0000313|EMBL:SFN32216.1, ECO:0000313|Proteomes:UP000183107};
RN [1] {ECO:0000313|Proteomes:UP000183107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp8 {ECO:0000313|Proteomes:UP000183107};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; FOVJ01000001; SFN32216.1; -; Genomic_DNA.
DR RefSeq; WP_074794126.1; NZ_FOVJ01000001.1.
DR AlphaFoldDB; A0A1I4Y2D7; -.
DR OrthoDB; 9775880at2; -.
DR Proteomes; UP000183107; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000183107};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 113..194
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 218..401
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 415 AA; 46889 MW; 48E6D528B4AB0FC4 CRC64;
MPLSDLAVRN AKPADKPYKL TDGDGLYLLV NSAGKYWRYD YRYLGKRKTL AFGVYPDVPL
ATRVEKDEET GRTRKVTGAR ELREEARQLL AQRIDPGTIK QARKREEKEL AASTFESVAR
EWHEKQSTNL EPKTAARILS ILRRNIFPAI GNTPIAQVTA ANLLSTIQKI EKRGTVSTAH
RAMQYCGQIF RYAIATGRAQ ADLSLVLKGA LTPFKEKHHA SITDPKKIRG LLLSLDGYDG
SFITKSALRI APLVFVRPVE LRHAEWSEID SDAAEWRIAA GKMKMKAVHL VPLSSQALTI
LRELHPHTGE GRFVFPSVRS YSRPMSENTV NAALRRLGYE KNEMTGHGFR SMASTILHEQ
GWPHEAIERQ LAHAERNKVS AAYNYAEHLP KRREMMQAWA DYLDELRAGR SYTVA
//
