ID   A0A1I4YL74_9MICO        Unreviewed;       419 AA.
AC   A0A1I4YL74;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE            EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE   AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN   ORFNames=SAMN05216219_0322 {ECO:0000313|EMBL:SFN38737.1};
OS   Mycetocola miduiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Mycetocola.
OX   NCBI_TaxID=995034 {ECO:0000313|EMBL:SFN38737.1, ECO:0000313|Proteomes:UP000198867};
RN   [1] {ECO:0000313|Proteomes:UP000198867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.11101 {ECO:0000313|Proteomes:UP000198867};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC         ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000799};
CC   -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC       {ECO:0000256|ARBA:ARBA00005297}.
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DR   EMBL; FOVM01000001; SFN38737.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4YL74; -.
DR   STRING; 995034.SAMN05216219_0322; -.
DR   Proteomes; UP000198867; Unassembled WGS sequence.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   InterPro; IPR004561; IsoChor_synthase.
DR   NCBIfam; TIGR00543; isochor_syn; 1.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF1; ISOCHORISMATE SYNTHASE MENF; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198867}.
FT   DOMAIN          161..410
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   419 AA;  44304 MW;  7AA99A62F9C19B7D CRC64;
     MTSPGTLPST QHLVVETQQV DDVRSLIALV DPQRPLLWLR KGRGLAGVGE ALRLEFSGPT
     RMQDAAAAWR EIAAAATVSD PLRMAGTGLV AFGTFAFADH SAQSSVLIVP QLLIGRRDGV
     TWVTRIRADD THEADVPANP RSTAFGPEYR IPLTAGAESA DGFLEHVTQA VERILDGELS
     KVVLSRDLTG RIPADADLRR VVSDLALGYP DCWTFAVDGL VGSSPETLVG VQDGSVTARV
     LAGTASRGAD AEADQRAAVN LVTSAKDQDE HQFAVQSVLA SLRPHTSHVL TSEMPFTLKL
     PNLWHLATDI EGTLTDDATS LDLIDALHPT AAVAGSPTPA AVALIDQLEP FDRGRYAGPI
     GWVGADGGGE WAIALRCAQV EPGGDVTAYA GCGIVGESVP EKELTETRMK FRPIVDAFG
//