ID   A0A1I4Z527_9ACTN        Unreviewed;       346 AA.
AC   A0A1I4Z527;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Transketolase {ECO:0000313|EMBL:SFN45381.1};
GN   ORFNames=SAMN04487980_1020113 {ECO:0000313|EMBL:SFN45381.1};
OS   Streptomyces sp. cf124.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761903 {ECO:0000313|EMBL:SFN45381.1, ECO:0000313|Proteomes:UP000198530};
RN   [1] {ECO:0000313|EMBL:SFN45381.1, ECO:0000313|Proteomes:UP000198530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF124 {ECO:0000313|EMBL:SFN45381.1,
RC   ECO:0000313|Proteomes:UP000198530};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOUV01000020; SFN45381.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I4Z527; -.
DR   Proteomes; UP000198530; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR   PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
FT   DOMAIN          36..201
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   346 AA;  35742 MW;  600B77C583C4DC6D CRC64;
     MTETTSPAKT ADPTAQATAE ATAETVTRPL VDAPVYDCRQ AFAEELIALA REDSRVVVVC
     NDSVGSSNLS GFRDEFPDRL INVGIAEQNM VGVGAGLANA GYVPFVSAAG PFLTGRALEQ
     IKADCAYSGH KVVLCGQSPG MAYGELGPTH HSVEDLSWLR AVADLTVVVP TDRAQTRAAV
     RWAHAHDGPS YLRVPRFKVP DVTPPGAPFA PGRALTLRDG GDVTLVAIGT MVPRALIAAD
     RLAADGISAR VLNTPFVDPL DETAILRAAA ETRAIVTAEE ATVSGGLGAA VASLTGQHSP
     VPLRLLGVSG FAPTGSPEGL LEHFGLTAGA MHRAAREALG LPSSAS
//