ID   A0A1I5AAB2_9MICO        Unreviewed;       378 AA.
AC   A0A1I5AAB2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Predicted naringenin-chalcone synthase {ECO:0000313|EMBL:SFN59270.1};
GN   ORFNames=SAMN05216219_1289 {ECO:0000313|EMBL:SFN59270.1};
OS   Mycetocola miduiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Mycetocola.
OX   NCBI_TaxID=995034 {ECO:0000313|EMBL:SFN59270.1, ECO:0000313|Proteomes:UP000198867};
RN   [1] {ECO:0000313|Proteomes:UP000198867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.11101 {ECO:0000313|Proteomes:UP000198867};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR   EMBL; FOVM01000003; SFN59270.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5AAB2; -.
DR   STRING; 995034.SAMN05216219_1289; -.
DR   OrthoDB; 9786288at2; -.
DR   Proteomes; UP000198867; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198867}.
FT   DOMAIN          76..216
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          235..371
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        157
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   378 AA;  39738 MW;  52BEFBB7C7ABC2F7 CRC64;
     MPAYIRTIQT ALPPTVLVQS EAREVFSEQA GLTRLGQRLV RTSFDGSGIE TRRSVIADFD
     ADAGVIDPLF FDSATGSLLA PSTRVRNDVY IREAGLLFFA AAEAALGACP GISAADVTHV
     VTVSCTGFYA PGPDYEVVRQ LGLSTATQRY NIGFMGCYAA FPALRAAAAF CAADPDAVVL
     VVSCELCTIH VRSSNDPDQI IASSVFGDGA AAAIVTGRAP ESDAPSLIID RLASDLTPVG
     EKDMAWTIGD SGFEMVLSAA VPKIIDVYIE GALKPLLAGE PDLGGDPATG IRHWAIHPGG
     RSILDKVEAK LGLSEEQLAP SRRILRDYGN MSSATVLFVL KDILEQKAPE GTDRVCAMAF
     GPGLTVETGL FTRVVAAS
//