ID   A0A1I5ATH9_9ACTN        Unreviewed;       446 AA.
AC   A0A1I5ATH9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cysteine synthase {ECO:0000313|EMBL:SFN65710.1};
GN   ORFNames=SAMN04487980_102752 {ECO:0000313|EMBL:SFN65710.1};
OS   Streptomyces sp. cf124.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761903 {ECO:0000313|EMBL:SFN65710.1, ECO:0000313|Proteomes:UP000198530};
RN   [1] {ECO:0000313|EMBL:SFN65710.1, ECO:0000313|Proteomes:UP000198530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF124 {ECO:0000313|EMBL:SFN65710.1,
RC   ECO:0000313|Proteomes:UP000198530};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; FOUV01000027; SFN65710.1; -; Genomic_DNA.
DR   RefSeq; WP_060885939.1; NZ_FOUV01000027.1.
DR   AlphaFoldDB; A0A1I5ATH9; -.
DR   Proteomes; UP000198530; Unassembled WGS sequence.
DR   GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR   CDD; cd00158; RHOD; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
PE   4: Predicted;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT   DOMAIN          354..445
FT                   /note="Rhodanese"
FT                   /evidence="ECO:0000259|PROSITE:PS50206"
SQ   SEQUENCE   446 AA;  48017 MW;  8E1EAE667AF6E292 CRC64;
     MRYDTITDAI GDTPLVRIDP AVHGLRNIDL YAKLEMLNPF GSLKDRAAWS MTRQDIAGAK
     ERGETIVELS SGNTAKALAL IAGLHGLPFK SVTNRMRVPE IKDLLLLLGA EIEELPGQTE
     CLDPTDTEDP LTLFHQRLNR PGGAHLHTDQ YFNALNTEAH ATGTGPEIIA DLDGRAPDWF
     IACVGTAGSS TGVARALRAH DPAVRVVGLV GRKGDFIPGI RTVDEVQEVG IFDPATYDTL
     ESVSADEAID GMLTLLRRCG LLAGPTGGAA YHGAVRHLAA VDAELTAADA GSTERKTAVF
     IVCDRVESYL GYVRQRRPDL LGRPPARNAL AAPTDSEIRS AKVIDVEEAQ KWIAEQRPLV
     IDLRGPFAYA ALHIDGSVNI VDELFEELVR GGLPFGRRQP VLLACPVGEK SARYAALLTR
     MGHPDVRSLS GGVIAWRDAG APLVRD
//