ID A0A1I5B2H2_9SPHN Unreviewed; 561 AA.
AC A0A1I5B2H2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=SAMN05428984_0157 {ECO:0000313|EMBL:SFN68709.1};
OS Sphingomonas sp. OK281.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1881067 {ECO:0000313|EMBL:SFN68709.1, ECO:0000313|Proteomes:UP000199378};
RN [1] {ECO:0000313|EMBL:SFN68709.1, ECO:0000313|Proteomes:UP000199378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK281 {ECO:0000313|EMBL:SFN68709.1,
RC ECO:0000313|Proteomes:UP000199378};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVZ01000001; SFN68709.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5B2H2; -.
DR STRING; 1881067.SAMN05428984_0157; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000199378; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..561
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011453500"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 429..556
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 561 AA; 61088 MW; 424060AC66C87E40 CRC64;
MRSRFCLHWL IGVVLMALAM MGASPADALA GRALSVCLLP ATPGLRADDL FRTPSRFDCT
TPQSRYGAGD FWIMSQRLPV DVASTPKLSA RAASVWQDRV TLYVLYADGA IRQTGFTSRT
AGRHLKLGAT LSLALPQHEA PPVRLLWHVE GAANLRGVVL GATLATEQQA AESEILLAAL
YASFGGMAIA LIVYNLALWG ALRQAFQPVY CLLVLCLLGY AFSSSAALGQ MVPGLDNNVR
LRINVVLLAI CASMALVFAR AFFERAVFEG WLRPATTAAL TILATTSIGF VLLAPWQIFW
LDRLLSLGYL PLIALVPAIL YRAWGVRSSY LWMFTLAWGV PIIFASLRVV NALGFMSWSF
WIDNSTMVSM MLEALLSSLA IAYRIRLLSL ERDEARLQEM AAQLLADTEP LTGLLNRRAF
LNRAIGRPGD QLLLIADVDH FKRVNDTIGH DGGDEVLRVI ARALRNAVPP GALVARIGGE
EFAILMDAAT PIPPDLILER LRSQRMPFDI AVTASIGCCT GPLLRETDWK ALYRGADRAL
FAAKGAGRNR SRDAGVLPLA A
//
