ID A0A1I5BFS6_9CLOT Unreviewed; 590 AA.
AC A0A1I5BFS6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=SAMN04488695_104193 {ECO:0000313|EMBL:SFN73564.1};
OS Proteiniclasticum ruminis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Proteiniclasticum.
OX NCBI_TaxID=398199 {ECO:0000313|EMBL:SFN73564.1, ECO:0000313|Proteomes:UP000181899};
RN [1] {ECO:0000313|EMBL:SFN73564.1, ECO:0000313|Proteomes:UP000181899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ML2 {ECO:0000313|EMBL:SFN73564.1,
RC ECO:0000313|Proteomes:UP000181899};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR EMBL; FOVK01000004; SFN73564.1; -; Genomic_DNA.
DR RefSeq; WP_074911931.1; NZ_FOVK01000004.1.
DR AlphaFoldDB; A0A1I5BFS6; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000181899; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW Reference proteome {ECO:0000313|Proteomes:UP000181899}.
FT DOMAIN 13..172
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 207..264
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 266..582
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 590 AA; 68250 MW; 5C8609207823BF5A CRC64;
MLYPISTPTR TLMDLSGIWR FSLEENHDPK SPLSHGEVMA VPGSFNEQGV LRKIRNHVGS
VWYEKDFEIF HKLLSERLVL RFGSATHYAK VYVNGKLVTE HKGGFMPFEA EINEYLVSGK
NRVTVEVNNI LDYSTLPVGN YKEENGVKKN QPNFDFFNYA GLHRPVKIYS TPKSYVEDLS
ITYDVEEAHA VVHFSETVKG DFDKVRFLVR DENQKVVYDG YEKDALIHHV ILWEPLKAYL
YEVEVHVEKN SEVVDIYTES FGIRTVEVKN NQFLINDKPF YFKGFGKHED FFVNGRGLNE
ALNVTDLNLM KWLGANSFRT AHYPYSEEMM RLCDRQGIVV IDETPAVGLM HGFNFALFGG
DGDKKKTFEV MNTREAHEQV LRELVARDKN LACVVMWSVA NEATTIEEGA EEYFAPLIKL
TKELDPQKRP VTQVLIMMSM PHNDVVSKHL DVICLNRYYG WYVNTGELEE AKTALRNELL
EWKRAYPNTP VMFTEYGADT VAGFHAVDDI PFTEEYQVRY LQANHEVFDE FDHVIGEQMW
NFADFETSVG IIRVQGNKKG LFTRQRHPKM AAHSVRDRWM SIPDFGYKNR
//
