ID A0A1I5BGB2_9SPHN Unreviewed; 241 AA.
AC A0A1I5BGB2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN ORFNames=SAMN05428984_0490 {ECO:0000313|EMBL:SFN73599.1};
OS Sphingomonas sp. OK281.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1881067 {ECO:0000313|EMBL:SFN73599.1, ECO:0000313|Proteomes:UP000199378};
RN [1] {ECO:0000313|EMBL:SFN73599.1, ECO:0000313|Proteomes:UP000199378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK281 {ECO:0000313|EMBL:SFN73599.1,
RC ECO:0000313|Proteomes:UP000199378};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC ECO:0000256|RuleBase:RU364092}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU364092}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
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DR EMBL; FOVZ01000001; SFN73599.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5BGB2; -.
DR STRING; 1881067.SAMN05428984_0490; -.
DR OrthoDB; 9778550at2; -.
DR Proteomes; UP000199378; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR01191; ccmC; 1.
DR PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01386; CCMCBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW Cell membrane {ECO:0000256|RuleBase:RU364092};
KW Cytochrome c-type biogenesis {ECO:0000256|RuleBase:RU364092};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364092};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 60..83
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 126..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT DOMAIN 29..183
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 241 AA; 26347 MW; D295BFF6D186D2AD CRC64;
MATLHAFANP ARFLKIAKPL TPALFWAGVA LIVLGCWAGL TQTPPDYLQG ETVRILYIHV
PAAWLGMGGW SGIAISSIMF LVWRHPLASV AARAIALPGA VFAALCLMTG SIWGRPTWGT
WWQWDGRLTS MLLLFFVYLG YMALAKADAD RGGDGRVPAL YGIAGSVLLP IIRYSVVWWN
TLHQGPSIGL TQSTIDGSIL WPLPIMLAGF TFVFAGIVLM RMRTMLAVSK SEARMRRMAR
G
//
