ID A0A1I5BXH5_9PROT Unreviewed; 802 AA.
AC A0A1I5BXH5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:SFN79370.1};
GN ORFNames=SAMN05216386_1861 {ECO:0000313|EMBL:SFN79370.1};
OS Nitrosospira briensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=35799 {ECO:0000313|EMBL:SFN79370.1, ECO:0000313|Proteomes:UP000183107};
RN [1] {ECO:0000313|Proteomes:UP000183107}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nsp8 {ECO:0000313|Proteomes:UP000183107};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOVJ01000003; SFN79370.1; -; Genomic_DNA.
DR RefSeq; WP_074796869.1; NZ_FOVJ01000003.1.
DR AlphaFoldDB; A0A1I5BXH5; -.
DR STRING; 1266925.GCA_000619905_02018; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000183107; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183107};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 549..742
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 802 AA; 88375 MW; 52FFFAAE5801830B CRC64;
MRTHILVFAV GIGLLQQQPM LPESAWAWAL LPGAAFAFLL LRTRSNGLIT IGKVLFAVVF
LAAGFFWAAA FAQWRLADVL PHEWEGRDIQ LIGVVAELPQ VNERNVRFAF DVEQVLTEDA
IVPARISLAW YDARGKRFKA EAAPPQIRAG ERWRITTRLK RPHGSVNPHG FDFEQWALER
NIRASGYVRE NDGNVRLDEM VNRPAYQVER LRQEVREQFI QALPGHVYTG VLVALAVGDQ
RAIPREQWQI FTRTGINHLM SISGLHVTMI SGLIFALVYW LWRRSHYLTL RLPARKAAAA
AGLTVALGYA LLAGFAIPAQ RTVYMLAVVA IALWLGRSTS VTAVLSWALL AVVVLDPWAV
LSPGFWLSFG AIAIIMLVSA GRIGRTHWLI GWARVQWAIT LSLIPPLLAM FQQVSMVSPV
ANAIAIPLVS LMVVPLTLLG TLPLLDFMLM PAHWLLSICM AAMQWMSDLP EAVWSQHAPP
AWTVAAAMAG IFWLMLPGGL GLGWGLGPRL TTGFPARWLG LVALLPMFLA LPPKPASGEL
WLTVLDVGQG LAVVARTENH TLLYDTGPGF SAEADSGSRT IVPFLRAEGV KHLDAMIVTH
ADLDHSGGAL SVLEAVPVGW VVSSLNEDHP IQLAASNKQQ CRAGQSWRWD GVRFDMLHPS
EQNYNNPRLK TNALSCVLKI TTTHGSVLLP ADIDKKSEYK LLADKGDALA STVLVAPHHG
SKTSSTSEFV SRVNPRLVIF TVGYRNRFGH PKKEVVERYQ ALGSRLLRSD TDGAVVLRFA
DKSIAVETGR ALKHRYWQDI PG
//
