ID A0A1I5DEI1_9FLAO Unreviewed; 428 AA.
AC A0A1I5DEI1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=UDP-N-acetyl-D-galactosamine dehydrogenase {ECO:0000313|EMBL:SFN97221.1};
GN ORFNames=SAMN04487989_107160 {ECO:0000313|EMBL:SFN97221.1};
OS Bizionia echini.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Bizionia.
OX NCBI_TaxID=649333 {ECO:0000313|EMBL:SFN97221.1, ECO:0000313|Proteomes:UP000198705};
RN [1] {ECO:0000313|EMBL:SFN97221.1, ECO:0000313|Proteomes:UP000198705}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23925 {ECO:0000313|EMBL:SFN97221.1,
RC ECO:0000313|Proteomes:UP000198705};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; FOVN01000007; SFN97221.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5DEI1; -.
DR STRING; 649333.SAMN04487989_107160; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000198705; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 322..421
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 428 AA; 46787 MW; 466739C6B126D8C5 CRC64;
MKKHQITIVG LGYVGLPLAV EFAKKYAVTG FDIYNKRVAE LRSGKDRTLE VTEPELQAVL
TDTLGDRGLY ITDSVEALAD SNIYIITVPT PTDSLNKPVF TPLIKASESI GKVLKKGDIV
IYESTVYPGV TEDICVPILA SVSGLTFNTD FYAGYSPERI NPGDKKHTVT KILKVTSGST
PEIATVVDDL YRSIITAGTH KAPSIKVAEA AKVIENSQRD INIAFVNELS KIFRLLDIDT
KAVLEAAGTK WNFIKFSPGL VGGHCIGVDP YYLAQKAIES GYNPEIILAG RKMNDSMGSY
VATETVKMMI KKGATIKGSR VLVLGITFKE NCPDIRNSRV IDIIREFETY DVSVDVFDPW
ASAEEVHHEY GLDLICDAAD LQTNYEGIVL AVSHNEFLGL DVMALKGDHG VVFDVKSLLP
NSQSDARL
//
