ID A0A1I5DVP9_9PSEU Unreviewed; 478 AA.
AC A0A1I5DVP9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=SAMN05421805_108290 {ECO:0000313|EMBL:SFO03278.1};
OS Saccharopolyspora antimicrobica.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=455193 {ECO:0000313|EMBL:SFO03278.1, ECO:0000313|Proteomes:UP000199398};
RN [1] {ECO:0000313|EMBL:SFO03278.1, ECO:0000313|Proteomes:UP000199398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPCC 201259 {ECO:0000313|EMBL:SFO03278.1,
RC ECO:0000313|Proteomes:UP000199398};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; FOUP01000008; SFO03278.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5DVP9; -.
DR STRING; 455193.SAMN05421805_108290; -.
DR Proteomes; UP000199398; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT DOMAIN 202..466
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 478 AA; 50341 MW; BB91C2C7E6005CCD CRC64;
MLDPVTESAA FGTTASLATV TDCKCRALAT PHGFGVGHHF GPGAYPPGVA TTSRPLVARS
RRLEPGDPRH DRPLLELLPG GSALSWVRDG AGLVGWGCAA RLEVSGPDRF ERADAWWQQL
CERAEVVDQV GLPGSGPVAF ASMAFADHPG HSALVVPEVV VGERDGVRWI TTIGDGTAEA
DEPEPVRPPG IISYSDGQLS ATGYRQAVAE AVGRMQEPGG LAKVVLAHDL LATTSEPLDM
RFLLHNLAAR YPSCWTFAVD GLIGATPELL LERTGYEVRS RVLAGTIWPR EGHSTEQLAA
ELLSSAKNRH EHAYAAESLA VRLRPFCSDL VAPDEPEVLQ LRNVLHLATN VEGKLSDADG
RAATLLRLAA AVHPTAAVGG TPTEDAVRLI SELEGMDRGR YAGPVGWLDG SGNGELGVAL
RCAQVEDAAA PGGETGRSGG KLRLFAGCGI VPDSDPDLEV AEAEAKLLPV REALEGLH
//
