ID   A0A1I5DYN9_9MICO        Unreviewed;       376 AA.
AC   A0A1I5DYN9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=SAMN05216219_3164 {ECO:0000313|EMBL:SFO04283.1};
OS   Mycetocola miduiensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Mycetocola.
OX   NCBI_TaxID=995034 {ECO:0000313|EMBL:SFO04283.1, ECO:0000313|Proteomes:UP000198867};
RN   [1] {ECO:0000313|Proteomes:UP000198867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.11101 {ECO:0000313|Proteomes:UP000198867};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOVM01000012; SFO04283.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5DYN9; -.
DR   STRING; 995034.SAMN05216219_3164; -.
DR   OrthoDB; 9779574at2; -.
DR   Proteomes; UP000198867; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198867}.
FT   DOMAIN          19..365
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   376 AA;  40881 MW;  6C60732351A50162 CRC64;
     MTFENQFLLP NGVDIAALPK ISLHDHLDGA LRPQTILELA DAVGVEVPET DADRLGQWFL
     TQCDAGNLVD YLKTFDLTTA VMQTEEGLTR VAREFVQDLA ADGVLYGEVR WAPEQHLARG
     LTLDQTVEAV QVGIEQGIDD AERAGRSIQI GQLVTAMRHA DRALEIAELA VRHLGNGVVG
     FDIAGAEAGF PASRHRVAFD FLAQEHVPVT VHAGEADGLD SIKSALFDGR ALRLGHGVRI
     AEDITVERSD DQGTYVSLGP TAQWVKDREI ALELSPSSNL QTGAIAAWGT DLADHPFDLL
     YQLGFKTTVN VDNRTMSGTS LTRELSLLSD AFAYDLDDLE VFQQNAASAA FLPLEDREEL
     AEAISAGFED AERYRA
//