ID   A0A1I5E2H2_9CLOT        Unreviewed;       976 AA.
AC   A0A1I5E2H2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Helicase conserved C-terminal domain-containing protein {ECO:0000313|EMBL:SFO05642.1};
GN   ORFNames=SAMN04488695_11310 {ECO:0000313|EMBL:SFO05642.1};
OS   Proteiniclasticum ruminis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Proteiniclasticum.
OX   NCBI_TaxID=398199 {ECO:0000313|EMBL:SFO05642.1, ECO:0000313|Proteomes:UP000181899};
RN   [1] {ECO:0000313|EMBL:SFO05642.1, ECO:0000313|Proteomes:UP000181899}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ML2 {ECO:0000313|EMBL:SFO05642.1,
RC   ECO:0000313|Proteomes:UP000181899};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOVK01000013; SFO05642.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5E2H2; -.
DR   STRING; 398199.SAMN05421804_101665; -.
DR   eggNOG; COG1061; Bacteria.
DR   Proteomes; UP000181899; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR   CDD; cd09204; PLDc_N_DEXD_b2; 1.
DR   CDD; cd18799; SF2_C_EcoAI-like; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR021835; DUF3427.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025202; PLD-like_dom.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF11907; DUF3427; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:SFO05642.1};
KW   Helicase {ECO:0000313|EMBL:SFO05642.1};
KW   Hydrolase {ECO:0000313|EMBL:SFO05642.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:SFO05642.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000181899}.
FT   DOMAIN          239..390
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          441..598
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   976 AA;  113010 MW;  3A1A14BDCA26C744 CRC64;
     MIANSELSKG LVHGFLDRTE TALESYKPRL IINDPERGEK VLTSIIQELS HCDAFYFSVA
     FITESGVTVL LNTLKELEEK GIQGKIIASQ YQNFSSPKAL KKLLELKNVE LRIVTQEAAK
     MHTKAYIFRK GEEYSIIVGS SNMTQSALCE NKEWNLKVSS SKEGAIVSNT IEEFNSMFTH
     ATIVDINWID AYSKIYELQK NINSTAEKTI EDHLSGKLLY LNAIKPNKMQ VNALQELEAT
     RNRQHEKTLI ISATGTGKTY LSAFDVKKFN PKRFLFVVHR EQIAKEALKS FRKVIGFEKT
     MSILSGNHKD FQADYIFTTI QTLSKEHIYR QFSPDDFEYI VIDEVHRAGA KSYKTIIDYF
     QPKFLLGMSA TPERTDGFDI FELFDHNIAY EIRLNDAMKE DLICPFHYFG ITELMVEGKI
     IDDQTQFNHL VSDARVQYIK EKVEFYGYSG SRVKGLVFCS RNEEAQNLSQ KFNDIGYRTL
     ALSGASSQEE RAEAVQRLGQ DENEGALDYI FTVDIFNEGV DIPEINQVVM LRPTKSAIIF
     VQQLGRGLRK VFGKEYVVVL DFIGNYDNNY LIPIALSGDQ SYNKDNIRRY VAESNRIIYG
     CSTINFDKIT RERIYKSIDH ADFNDLKIIK ESYQDLKNRL GRIPLLTEFI KYDVIDIERI
     FAKTGSYHNF LRKYEKDYQI SLNTEEEKFI EFISLKYVNG KRPHELEFIK LLLNEESAVL
     VKLEDLLFEK YRIEVNKNTR VNLINQMTQN FATGSSKSTF AKAIFIEKEG QDYKRSSAFL
     RCLQNSVFQQ MVMELLNIGL RKYEERYSNH YRETNFVLNE KYTYEDVCRL LDWSKNEVPL
     NIGGYKFDKE TKTFPVFINY HKDDDISETI QYHDEFFSPS EFLAFSKSGR TIQSDDVQTI
     YSAKDLGVEI LLFVRKDKTD KTSKEFYFLG KIDAIGSPVQ AKMRGTNVNV VKIRYKLDVP
     VRDDLYDYIT QEKIAD
//