ID A0A1I5E7D6_9BACT Unreviewed; 575 AA.
AC A0A1I5E7D6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SFO07469.1};
GN ORFNames=SAMN04488519_103327 {ECO:0000313|EMBL:SFO07469.1};
OS Algoriphagus ornithinivorans.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Algoriphagus.
OX NCBI_TaxID=226506 {ECO:0000313|EMBL:SFO07469.1, ECO:0000313|Proteomes:UP000199564};
RN [1] {ECO:0000313|Proteomes:UP000199564}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15282 {ECO:0000313|Proteomes:UP000199564};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOVW01000003; SFO07469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I5E7D6; -.
DR STRING; 226506.SAMN04488519_103327; -.
DR Proteomes; UP000199564; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 451..508
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 516..575
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 575 AA; 63170 MW; FCCF7AEE43FBF828 CRC64;
MSNQNFILIL SGIIGVISGL AAVILKQGVH AIQNFLTEGF YVEYANFMYI IYPIIGIAAA
FLIGKFLFKD VGGHGIPDVL FTISKKQSLI PRVKTYSRVI TSALTVGFGG SVGLEAPMLV
TGSAIGSNIG VLVHLNSKKR TLLIGCGAAG AISAIFGAPI GAVIFAIEVI LMEISTASFI
PLLIASVTGS LTSMLLIGED SVFNFNLQEE FRAAHMPYYL LLGIFCGIVS LYFSKAVVRT
EKIMEGLESQ TIRILYGGAM LGFMLFFFPP IYGEGYDTLN LLIDGNSNQL LEKSPFFSAI
ENPYMILIFL ALIILIKPIA SALTLSAGGS GGIFAPSLYV GGLVGFLFAF GKNMLGIHIP
LPLAHFTLVA MCGVMAGVQH APLSAIFLIA EITGGYELFV PLMFVSAISY ITTTYYQKDS
LYIQQLKEKG KQLPETKDQE LLDMIDISHV IERDLLPIHP ESKLKDLIDL VKISKRNIFP
VVDENKILRG IITLDDIRDI MFDLEKQENT QIRSLMHSPP EILLATENMQ KAMEKFEKSG
AWNLPVVEDG RYLGFVSKSR IFNSYRKRLI RQRQD
//
