ID A0A1I5ELU1_9ACTN Unreviewed; 451 AA.
AC A0A1I5ELU1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Multidrug efflux pump subunit AcrA (Membrane-fusion protein) {ECO:0000313|EMBL:SFO12326.1};
GN ORFNames=SAMN04489713_104179 {ECO:0000313|EMBL:SFO12326.1};
OS Actinomadura madurae.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=1993 {ECO:0000313|EMBL:SFO12326.1, ECO:0000313|Proteomes:UP000183413};
RN [1] {ECO:0000313|EMBL:SFO12326.1, ECO:0000313|Proteomes:UP000183413}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43067 {ECO:0000313|EMBL:SFO12326.1,
RC ECO:0000313|Proteomes:UP000183413};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOVH01000004; SFO12326.1; -; Genomic_DNA.
DR RefSeq; WP_075021057.1; NZ_UAPP01000009.1.
DR AlphaFoldDB; A0A1I5ELU1; -.
DR STRING; 1993.SAMN04489713_104179; -.
DR GeneID; 73573490; -.
DR eggNOG; COG0845; Bacteria.
DR InParanoid; A0A1I5ELU1; -.
DR OrthoDB; 3518416at2; -.
DR Proteomes; UP000183413; Unassembled WGS sequence.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000183413};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..451
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039486553"
FT DOMAIN 60..100
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
SQ SEQUENCE 451 AA; 45063 MW; 5CECBFD36D3DC41E CRC64;
MASRRYVPVL AAGALLAGVL SACTGGGGDG GIRLGRVERA DVSEVVEAPA TVSARATAVL
RSPAEGTIAR LYVADGDPVD EGDVLAKISS PGAREQLAQA LEADRSASAG GGVPEGLDLS
EFQRRTDRTA RDGFAAARKI ALRIPDLKER ALVLAGITRA EGQYRTASAA ARTAVARLNA
GLGSVGATIS SITAAQRVQT RAAVRTARRT VDALTIKAPF DGIAGLGGPA GGAPGLGDVL
DRLPQGARSQ AGGLTGLGNL GGGAAKDASA IAAGAPVSGG DAVITVTDVS TLALTADVDE
TDVLQVAKGV EAEAEFDAVE GGTYEAEVTG VGVTPKESSG GGVTYKVTLA LGRGALAGGG
TAPRPKPGMS AVVNLKVRDV RNVLSVPSSA IVTSGRESVV WAVSDGRAQR RVVGLGAEGD
ATVQITRGLR EGESIVVRGA DSVKQGQELG R
//
