ID   A0A1I5EN15_9ACTN        Unreviewed;       331 AA.
AC   A0A1I5EN15;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Cell wall-associated hydrolase, NlpC family {ECO:0000313|EMBL:SFO12912.1};
GN   ORFNames=SAMN04489713_104202 {ECO:0000313|EMBL:SFO12912.1};
OS   Actinomadura madurae.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=1993 {ECO:0000313|EMBL:SFO12912.1, ECO:0000313|Proteomes:UP000183413};
RN   [1] {ECO:0000313|EMBL:SFO12912.1, ECO:0000313|Proteomes:UP000183413}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43067 {ECO:0000313|EMBL:SFO12912.1,
RC   ECO:0000313|Proteomes:UP000183413};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C40 family.
CC       {ECO:0000256|ARBA:ARBA00007074}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOVH01000004; SFO12912.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I5EN15; -.
DR   STRING; 1993.SAMN04489713_104202; -.
DR   eggNOG; COG0791; Bacteria.
DR   InParanoid; A0A1I5EN15; -.
DR   Proteomes; UP000183413; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR   InterPro; IPR000064; NLP_P60_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   PANTHER; PTHR47359:SF3; NLPC_P60 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47359; PEPTIDOGLYCAN DL-ENDOPEPTIDASE CWLO; 1.
DR   Pfam; PF00877; NLPC_P60; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS51935; NLPC_P60; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:SFO12912.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183413};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..331
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039288426"
FT   DOMAIN          216..331
FT                   /note="NlpC/P60"
FT                   /evidence="ECO:0000259|PROSITE:PS51935"
FT   COILED          49..111
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          158..199
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   331 AA;  35799 MW;  583D79628DDD5CE6 CRC64;
     MQRSRSASLS RFRGRAAVVA GALIAVSAAP HAITPQKIAV AHADPEPSTK ELRAKALKLA
     DQLEQLTEQY NGLRVKLSQS QRAAKVATEN AERQEKSLEE LRQKVGALAA TSYMQGGSDP
     TVSFVASQDP QAVLDQAATL HYFAKQDSTQ VLGLMQAMQS AQRARKSAEA RAKQVKELRT
     QLESQRKKVT ETYEKVRGKL VDKDPTQLAK LPVVGTGKAA QALRYAMGKI GRPYVWGAAG
     PSTFDCSGLT MWAYKQVGIN LPHYTGSQWN AGTHVSRGQL QAGDLVFFYS DLHHMGMYVG
     DGKMLHAPQT GDVVKIAPMA GRPFAGGVRV A
//