ID A0A1I5EQ58_9CLOT Unreviewed; 208 AA.
AC A0A1I5EQ58;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RNA polymerase sigma factor SigS {ECO:0000256|ARBA:ARBA00021245};
GN ORFNames=SAMN04488695_1193 {ECO:0000313|EMBL:SFO13151.1};
OS Proteiniclasticum ruminis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Proteiniclasticum.
OX NCBI_TaxID=398199 {ECO:0000313|EMBL:SFO13151.1, ECO:0000313|Proteomes:UP000181899};
RN [1] {ECO:0000313|EMBL:SFO13151.1, ECO:0000313|Proteomes:UP000181899}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ML2 {ECO:0000313|EMBL:SFO13151.1,
RC ECO:0000313|Proteomes:UP000181899};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. Sigma-S contributes to the protection against external
CC stress, thus playing a role in cellular fitness and survival.
CC {ECO:0000256|ARBA:ARBA00024701}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|ARBA:ARBA00007788}.
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DR EMBL; FOVK01000019; SFO13151.1; -; Genomic_DNA.
DR RefSeq; WP_074913080.1; NZ_FOVK01000019.1.
DR AlphaFoldDB; A0A1I5EQ58; -.
DR STRING; 398199.SAMN05421804_1143; -.
DR eggNOG; COG1595; Bacteria.
DR OrthoDB; 9783788at2; -.
DR Proteomes; UP000181899; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.20.120.1810; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR016371; RNA_pol_sigma-H_factor.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF1; RNA POLYMERASE SIGMA-H FACTOR; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR PIRSF; PIRSF002939; RNA_polymerase_sigma-H_factor; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR PROSITE; PS00715; SIGMA70_1; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000181899};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 54..67
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
SQ SEQUENCE 208 AA; 24176 MW; 6A4D6E3CF71DC91B CRC64;
MLDDKKYKSL SDEEIVFLAQ NGDKRASEFI TAKYLPYVRN KSRAYFLVGG EVEDIMQEGL
IGLYEAIQDY SDSKQASFKT FMDICVTRQI MTALKAASRQ KHIPLNTYVS LNKPLFQEET
DRNFQDTLIT EKVEDPESLF IDVEKTIEIN KEIERSLSEF EYKVLRLYLQ GVSYVRIAKV
LEKEEKAIDN AIQRIRKKLS KNLMESTS
//
